Results 141 to 150 of about 31,184 (259)

Role of additional topotecan injections (plus two) in reducing recurrence rate in retinoblastoma of group D and group E patients: a retrospective study

BMJ Open Ophthalmology
Objective To evaluate the effectiveness of administering additional intravitreal topotecan injections (plus two) in reducing the recurrence rate in patients with advanced retinoblastoma (RB).Methods and analysis This retrospective, non-comparative and ...
Qiang Liu, Jiang Qian, Haifeng Chen, Kang Xue, Ruiqi Ma, Xintong Lin, Zhuqing Zheng   +6 more
doaj   +1 more source

Dual‐Targeting Cuproptosis and Mitophagy via a Flavopiridol‐Copper Nanoplatform Potentiates Immunotherapy Against Uveal Melanoma

Advanced Science, Volume 13, Issue 32, 9 June 2026.
This study develops a GSH‐responsive nanoplatform, NP@Fla‐Cu, to co‐activate cuproptosis and excessive mitophagy in uveal melanoma. The nanoplatform enhances tumor‐specific copper delivery, depletes antioxidant defenses, and remodels the tumor immune microenvironment.
Hong Ren, Zhihong Deng, Sheng Lu, Jing Zhang, Wenbin Liu, Jia Tan   +5 more
wiley   +1 more source

Endophthalmitis after intravitreal injections: incidence, presentation, management, and visual outcome

, 2015
PURPOSE: To report the incidence and characteristics of endophthalmitis after intravitreal injections of anti vascular endothelial growth factor agents or corticosteroids and to describe the clinical and bacteriologic characteristics, management, and ...
Bron, Alain, Aho-Glélé, Ludwig S., Creuzot Garcher, Catherine, Koehrer, Philippe, Dossarps, Denis   +4 more
core   +1 more source

Decoding the Factor H‐Related Proteins: Gatekeepers of Complement Dysregulation in AMD

European Journal of Immunology, Volume 56, Issue 6, June 2026.
This review will explore the role of the factor H‐related (FHR) proteins in age‐related macular degeneration (AMD), their accumulation in the outer blood/retinal barrier, and how they may contribute to barrier dysfunction and inflammation. ABSTRACT Age‐related macular degeneration (AMD) is the third most common form of blindness in the Western world ...
Jiaqi Tang, Nathalie Zgoda, Simon J. Clark   +2 more
wiley   +1 more source

Shifting From Systemic to Precision‐Targeted Complement Therapies: Opportunities and Hurdles

European Journal of Immunology, Volume 56, Issue 6, June 2026.
Complement therapeutics have expanded considerably, but systemic inhibitors remain limited by infection risks, breakthrough events, and loss of physiological functions. Emerging targeted approaches aim for organ‐, tissue‐, or cell‐specific modulation of complement activity, potentially offering greater precision while reducing treatment burden and ...
Marco Mannes, Wioleta M. Zelek, Leendert A. Trouw   +2 more
wiley   +1 more source

Evaluation of Anxiety Levels in Patients Who Underwent Intravitreal Injections

, 2016
Amaç: İntravitreal enjeksiyon yapılan hastalarda enjeksiyon öncesi ve sonrası anksiyete düzeyini değerlendirmek ve intravitreal enjeksiyon sayısı ile anksiyete düzeyi arasındaki ilişkiyi araştırmak.Gereç ve Yöntem: Bu çalışmaya diyabetik maküla ödemi ...
Ayşen Topalkara, Ayşe Özeç Vural, Mustafa İlker Toker, Mustafa Kemal Arıcı, Feyza Dursun Gülaç, Haydar Erdoğan, Ayhan Dursun, Derya Güliz Mert, Erman Bozali   +8 more
core  

Refractive changes after intravitreal ranibizumab injections for diabetic macular oedema

, 2018
Purpose: The purpose of this study was to evaluate refractive changes after intravitreal ranibizumab injections for the treatment of diabetic macular oedema.
Chatzipantelis, Athanasios, Dimitriou, E., Dimitriou, Eleni, Chatziralli, Irini, Mpourouki, Evgenia, Chatziralli, I., Theodossiadis, Panagiotis, Mpourouki, E., Theodossiadis, G., Theodossiadis, George, Theodossiadis, P., Chatzipantelis, A.   +11 more
core  

Associations Between Initial Glycated Hemoglobin at Diabetes Diagnosis, Longitudinal Changes and Medication Effects, and the Severity and Progression of Sight‐Threatening Diabetic Retinopathy

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 6, June 2026.
ABSTRACT Diabetic retinopathy (DR) is a leading cause of vision impairment in patients diagnosed with Type 2 diabetes mellitus (T2DM). Awareness of risk factors is necessary to reduce or prevent harmful effects of DR such as irreversible vision loss, and to help ensure early treatment.
Yu‐Chi Sung, Yu‐Kuang Chen, Ching‐An Chen, Pei‐Kang Liu, Kai‐Chun Cheng, Wei‐Shan Chang, Chia‐Li Tseng, Hui‐Min Hsieh, Shwu‐Jiuan Sheu   +8 more
wiley   +1 more source

Effects Of Music Therapy On Intravitreal Injections

, 2012
This randomized clinical trial investigates the effects of music therapy on anxiety, perceived pain and satisfaction in patients undergoing intravitreal injections in the outpatient setting.
Chen, Xuejing
core  

Innovative Drug Delivery Systems for the Treatment of Glaucoma

MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
This review aims to provide a comprehensive overview of current topical drug delivery strategies for ocular hypotensive agents in glaucoma therapy. Additionally, it discusses the potential impact of emerging nanotechnological and biomaterial‐based systems in shaping the future of ophthalmic drug delivery, with an emphasis on enhancing efficacy, safety,
Jing Chu, Junzhi Li, Zhenlin Chen, Jinyu Zhang, Siqi Feng, Jiaying Huang, Yawen Chu, Xue Zhou, Wei Wang, Shangsi Chen   +9 more
wiley   +1 more source