Results 141 to 150 of about 1,525,008 (304)

Repeated Treatment for Macular Edema in Vein Occlusion by Intravitreal Implant of Dexamethasone

open access: yesCase Reports in Ophthalmology, 2012
Background: Macular edema (ME) treatment has benefited from the recent intravitreal pharmacotherapy development of an intravitreal implant of dexamethasone (Ozurdex®, Allergan, Irvine, Calif., USA).
Frederic Matonti   +3 more
doaj   +1 more source

Intravitreal injections: A review of pharmacological agents and techniques

open access: yes, 2016
Over the past three decades, intravitreal delivery of pharmacotherapeutic agents has advanced tremendously with many drugs being developed solely for intravitreal use.
Hasanain Shikari, Preetam M Samant
semanticscholar   +1 more source

Stage‐Associated Microglial Subpopulations and Dynamics in Vascular Pathogenesis of Oxygen‐Induced Retinopathy

open access: yesCell Proliferation, EarlyView.
In the oxygen‐induced retinopathy (OIR) mouse model, two distinct microglial subpopulations play opposing roles: highly glycolytic microglia (HGM) promote neovascular formation via Pkm2, while Mrc1/CD206‐positive phagocytosis‐associated microglia (PAM) facilitate its regression.
Yuan Ma   +20 more
wiley   +1 more source

Initial intravitreal injection of high-dose ganciclovir for cytomegalovirus retinitis in HIV-negative patients

open access: yesBMC Ophthalmology, 2018
Background The purpose of this study is to examine the clinical outcomes achieved by using initial high-dose intravitreal ganciclovir injections to treat cytomegalovirus retinitis in patients without human immunodeficiency virus (HIV) infection.
Zhuyun Qian   +3 more
doaj   +1 more source

Erythrocyte deformability correlates with microvascular ischemia and disease severity in diabetic retinopathy

open access: yesJournal of Diabetes Investigation, EarlyView.
Under physiological conditions, deformable erythrocytes pass smoothly through the capillary network, maintaining retinal capillary perfusion (A). In pathological conditions, reduced erythrocyte deformability causes irregular passage and stagnation within capillaries, resulting in localized blood flow stasis and microvascular congestion, leading to ...
Ye Eun Han   +5 more
wiley   +1 more source

Evaluation for endotoxin in intraocular materials used during phacoemulsification surgery using a recombinant factor C assay

open access: yesVeterinary Ophthalmology, Volume 28, Issue 2, Page 481-485, March 2025.
Abstract Objective Cataract surgery remains the sole method to resolve blindness secondary to cataract formation. One complication includes fibrin web formation post‐operatively. This study aimed to investigate the presence of endotoxin within materials used during cataract surgery as a possible cause of fibrin web phenomenon. Methods Preservative‐free
Taylor A. Opgenorth   +3 more
wiley   +1 more source

The intravitreal injection: Variations in regulations, cost and reimbursement in Europe [PDF]

open access: yes, 2018
Zusammenfassung: HINTERGRUND: Grosse prospektive, randomisierte, kontrollierte klinische Studien haben für den intravitrealen Einsatz von Inhibitoren des vaskulären endothelialen Wachstumsfaktors (VEGF) klare Behandlungsvorgaben mit höchstem ...
Becker, M.   +3 more
core  

Techniques for subretinal injections in animals

open access: yesVeterinary Ophthalmology, Volume 28, Issue 2, Page 506-518, March 2025.
Abstract Subretinal injections are not commonly performed during clinical treatment of animals but are frequently used in laboratory animal models to assess therapeutic efficacy and safety of gene and cell therapy products. Veterinary ophthalmologists are often employed to perform the injections in the laboratory animal setting, due to knowledge of ...
Ryan F. Boyd, Simon M. Petersen‐Jones
wiley   +1 more source

Patients' tolerance of bimanual lid retraction versus a metal speculum for intravitreal injections

open access: yesClinical Ophthalmology, 2016
Khadijah Alattas Department of Ophthalmology, College of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia Objective: To compare patients’ acceptance of and correlate their pain level for bimanual versus metal speculum fixation in ...
Alattas K
doaj  

Efficacy of 0.2% povidone‐iodine and 0.1% polyhexamethylene biguanide as preoperative antiseptics in equine ophthalmic procedures

open access: yesVeterinary Ophthalmology, Volume 28, Issue 2, Page 438-447, March 2025.
Abstract Objective This retrospective study evaluates the efficacy of povidone‐iodine (PI) and polyhexamethylene biguanide (PHMB) as preoperative antiseptics in equine ophthalmic procedures. Animals Studied Horses that underwent routine ophthalmic surgery and procedures.
Anna Farkas   +4 more
wiley   +1 more source

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