Results 41 to 50 of about 39,591 (271)

A Case of Sustained Intraocular Pressure Elevation after Multiple Intravitreal Injection of Ranibizumab and Aflibercept for Neovascular Age-Related Macular Degeneration

Case Reports in Ophthalmology, 2016
Intravitreal injections of anti-vascular endothelial growth factor (VEGF) agents are widely used to treat neovascular age-related macular degeneration (nAMD).
Hisashi Matsubara, Ryohei Miyata, Maki Kobayashi, Hideyuki Tsukitome, Kengo Ikesugi, Mineo Kondo   +5 more
doaj   +1 more source

Comparative lipid profiling dataset of the inflammation-induced optic nerve regeneration. [PDF]

, 2019
In adult mammals, retinal ganglion cells (RGCs) fail to regenerate following damage. As a result, RGCs die after acute injury and in progressive degenerative diseases such as glaucoma; this can lead to permanent vision loss and, eventually, blindness ...
Bhattacharya, Sanjoy K, Caprioli, Joseph, Kwong, Jacky MK, Piqueras, Maria, Stark, David T, Trzeciecka, Anna   +5 more
core   +1 more source

Therapeutic approaches with intravitreal injections in geographic atrophy secondary to age-related macular degeneration: current drugs and potential molecules [PDF]

, 2019
The present review focuses on recent clinical trials that analyze the efficacy of intravitreal therapeutic agents for the treatment of dry age-related macular degeneration (AMD), such as neuroprotective drugs, and complement inhibitors, also called ...
Cerini, Alberto, Greco A., La Cava M, Lambiase A, Limoli PG, Nebbioso M   +5 more
core   +1 more source

An in vivo evaluation of Brilliant Blue G in animals and humans [PDF]

, 2008
Background/Aims: To evaluate the retinal toxicity of Brilliant Blue G (BBG) following intravitreal injection in rat eyes and examine the biocompatibility and the staining properties in humans.Methods: BBG was injected into the 11 rat eyes to evaluate ...
Fiedorowicz, M., Grüterich, Martin, Haritoglou, Christos, Kampik, Anselm, May, C. A., Nentwich, Martin M., Priglinger, Siegfried G., Remy, M., Schuettauf, F., Schumann, Ricarda G., Thaler, S.   +10 more
core   +1 more source

Intravitreal Anti-VEGF Drugs and Signals of Dementia and Parkinson-Like Events: Analysis of the VigiBase Database of Spontaneous Reports [PDF]

, 2020
Introduction: Since vascular endothelial growth factor (VEGF) regulates several aspects of the central nervous system, particularly in dopaminergic neurons, VEGF inhibitors may be linked to Parkinson-like events and dementia, or variants of these ...
Avery, Bergvall, Caballero, Campochiaro, Cutroneo, de Jong, De Rossi, Evans, Ferrara, Ferrara, Kumar, Lim, Lindquist, McColl, Meyer, Robinson, Sanchez, Sharma, Sheikh, Simó, Steen, Storkebaum, Sultana, Thulliez, Tian, Trifirò, Ueta, Wong, Yasuhara, Ylä-Herttuala, Zachary   +30 more
core   +4 more sources

Integrated results from the COPERNICUS and GALILEO studies. [PDF]

, 2017
OBJECTIVES: To report on the efficacy and safety of intravitreal aflibercept in patients with macular edema secondary to central retinal vein occlusion (CRVO) in an integrated analysis of COPERNICUS and GALILEO.
Ahlers, Christiane, Asmus, Friedrich, Boyer, David S., Clark, W. Lloyd, Haller, Julia A., Holz, Frank G., Korobelnik, Jean-Francois, Ogura, Yuichiro, Pielen, Amelie, Rittenhouse, Kay D., Saroj, Namrata, Stemper, Brigitte, Vitti, Robert, Zeitz, Oliver   +13 more
core   +3 more sources

Comparative incidence of endophthalmitis after intravitreal dexamethasone implant versus anti-VEGF injections: a retrospective study

International Journal of Retina and Vitreous
Background Endophthalmitis is a rare but vision-threatening complication of intravitreal injections. Intravitreal dexamethasone implants and anti–vascular endothelial growth factor (anti-VEGF) agents are widely used, yet comparative real-world ...
Iza D. Zabaneh, Tanner Dunn, Kortney Dunn, Patrick Williams   +3 more
doaj   +1 more source

Treatment as required versus regular monthly treatment in the management of neovascular age-related macular degeneration: a systematic review and meta-analysis [PDF]

, 2015
Background: To investigate whether treatment as required ‘pro re nata’ (PRN) versus regular monthly treatment regimens lead to differences in outcomes in neovascular age-related macular degeneration (nAMD).
Agostini, Hansjuergen, Ehlken, Christoph, Loke, Yoon K., Oeller, Patrick, Rücker, Gerta, Schmucker, Christine M., Sommer, Harriet, Virgili, Gianni   +7 more
core   +3 more sources

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Comparison between “early” or “late” intravitreal injection of dexamethasone implant in branch (BRVO) or central (CRVO) retinal vein occlusion: six months follow-up [PDF]

, 2017
AIM: The aim of this study was to compare early and late injections of intravitreal dexamethasone implant in patients affected by central retinal vein occlusion (CRVO) or branch retinal vein occlusion (BRVO) with a six-months follow-up.
AUTOLITANO, MONICA, BASILI, Stefania, LA TORRE, Giuseppe, LENZI, TOMMASO, PACELLA, Elena, PACELLA, FERNANDA, Pascarella, Antonella   +6 more
core   +1 more source