Results 51 to 60 of about 39,591 (271)

Subconjunctival anaesthesia for intravitreal injections [PDF]

Eye, 2013
Sir, We read with interest the paper by Lyall et al,1 who report the results of an observational study of infective endophthalmitis in the United Kingdom following intravitreal anti-VEGF injection. Using 200 patients selected from 10 control centres, the authors identified 3 endophthalmitis patients, compared to 1 control patient, who had ...
Alexander, P., Sahu, D., Lotery, A.J.
openaire   +3 more sources

Modular Control of PEG‐Poly(2‐Oxazoline) Co‐Assembly Enables Tunable Aggregate Properties for Intraocular Pressure Management

Advanced Healthcare Materials, EarlyView.
A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka, Shohei Morikawa, Shigehito Osawa   +2 more
wiley   +1 more source

An eighteen-month follow-up study on the effects of intravitreal dexamethasone implant in diabetic macular edema refractory to anti-VEGF therapy [PDF]

, 2016
AIM: To evaluate the long-term efficacy and safety of dexamethasone implants in subjects affected by diabetic macular edema (DME) resistant to anti-vascular endothelial growth factor (VEGF) therapy. METHODS: Thirty-two DME patients were enrolled.
Carnovale, Anna, Mastromatteo, Alessandra, Mollicone, Antonella, Pacella, Elena, Pacella, Fernanda, Romano, Maria Rosaria, Tarquini, Giovanna, Turchetti, Paolo   +7 more
core   +1 more source

Topical antibiotics and intravitreal injections [PDF]

Acta Ophthalmologica, 2017
AbstractThere is increasing evidence that topical antibiotics, given before and/or after intravitreal injections, are ineffective in preventing endophthalmitis and are possibly harmful. In addition to the lack of efficacy and increased development of resistant organisms, the use of topical antibiotics adds significantly to the cost of delivering ...
Hunyor, Alex P., Merani, Rohan, Darbar, Archie, Korobelnik, Jean François, LANZETTA, Paolo, Okada, Annabelle A.   +5 more
openaire   +3 more sources

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

Cost effectiveness of treatments for wet age-related macular degeneration [PDF]

, 2011
Age-related macular degeneration (AMD) is a leading cause of blindness in people aged >= 50 years. Wet AMD in particular has a major impact on patient quality of life and imposes substantial burdens on healthcare systems.
Annemans, Lieven, Gallagher, Meghan, Mitchell, Paul, Thomas, Simu, White, Richard   +4 more
core   +1 more source

Intravitreal silicone oil droplet after intravitreal injection

Journal of Retina-Vitreous, 2022
Currently, anti-vascular endothelial growth factor agents (anti-VEGF) are frequently used in the treatment of diseases such as age-related macular degeneration and diabetic macular edema. In our study, we discussed three cases in which intravitreal silicone oil droplets were detected during the follow-up after intravitreal anti-VEGF agent ...
Çetin, Ebru Nevin, Pekel, Gökhan, Akbulut, Selen   +2 more
openaire   +2 more sources

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

Management of anterior chamber dislocation of a dexamethasone intravitreal implant: a case report [PDF]

, 2016
Background Ozurdex is a 700 mcg dexamethasone intravitreal implant, approved for the management of macular edema secondary to retinal vein occlusion, and other related pathoglogiesAnterior chamber dislocation of Ozurdex represents an uncommon ...
AGOSTINELLI, Enzo, CARLESIMO, Sandra Cinzia, Forastiere, Michele, NEBBIOSO, Marcella, PACELLA, Elena, PACELLA, FERNANDA, SECONDI, ROBERTO   +6 more
core   +1 more source

A Multiple Stakeholder Multicriteria Decision Analysis in Diabetic Macular Edema Management: The MULTIDEX‑EMD Study [PDF]

, 2020
Background The clinical and economic management of retinal diseases has become more complex following the introduction of new intravitreal treatments. Multicriteria decision analysis (MCDA) offers the potential to overcome the challenges associated with ...
Casado, Miguel Ángel, Cervera, Enrique, de Andrés‑Nogales, Fernando, García Layana, Alfredo, Ignacio García, Emilio Francisco, Llorente, Iñaki, Martínez Olmos, José, Martínez Sesmero, José Manuel, Martínez, Mercedes, Mur, Carlos, Ortiz, Pere, Peralta, Gemma, Poveda, José Luis, Rodríguez Maqueda, Mariano, Ruiz Moreno, José María, Trillo, José Luis, Udaondo, Patricia, Zarranz Ventura, Javier, Zulueta, Jacinto, Álvarez, Eloísa   +19 more
core   +3 more sources