Results 71 to 80 of about 8,419,741 (275)

Network localization of regional intrinsic neural activity alterations in migraine and their neurochemical correlates

open access: yesFrontiers in Neurology
BackgroundMigraine is a prevalent and disabling neurological disorder. Resting-state functional magnetic resonance imaging (rs-fMRI) studies have investigated regional intrinsic neural activity alterations in migraine but have often yielded inconsistent ...
Hu-Cheng Yang   +10 more
doaj   +1 more source

Frequency-specific alterations in intrinsic low-frequency oscillations in newly diagnosed male patients with obstructive sleep apnea

open access: yesFrontiers in Neuroscience, 2022
PurposePrevious studies found abnormal low-frequency spontaneous brain activity related to cognitive impairment in patients with obstructive sleep apnea (OSA).
Yaping Zeng   +13 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

The intrinsic activity of the brain and its relation to levels and disorders of consciousness [PDF]

open access: yes, 2017
peer reviewedScience and philosophy still lack an overarching theory of consciousness. We suggest that a further step toward it requires going beyond the view of the brain as input-output machine and focusing on its intrinsic activity, which may express ...
Laureys, Steven   +2 more
core   +3 more sources

Altered intrinsic regional brain spontaneous activity and subjective sleep quality in patients with chronic primary insomnia: a resting-state fMRI study

open access: yesNeuropsychiatric Disease and Treatment, 2014
Xi-Jian Dai,1,2 De-Chang Peng,1 Hong-Han Gong,1 Ai-Lan Wan,3 Xiao Nie,1 Hai-Jun Li,1 Yi-Xiang J Wang2 1Department of Radiology, The First Affiliated Hospital of Nanchang University, Nangchang, Jiangxi, People’s Republic of China; 2Department of ...
Dai XJ   +6 more
doaj  

Dynamic models of brain imaging data and their Bayesian inversion [PDF]

open access: yes, 2010
This work is about understanding the dynamics of neuronal systems, in particular with respect to brain connectivity. It addresses complex neuronal systems by looking at neuronal interactions and their causal relations.
Sousa Cardoso Costa Marreiros, A.
core  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Intrinsic dynamic shapes responses to external stimulation in the human brain

open access: yeseLife
Sensory stimulation of the brain reverberates in its recurrent neural networks. However, current computational models of brain activity do not separate immediate sensory responses from this intrinsic dynamic.
Maximilian Nentwich   +4 more
doaj   +1 more source

Machine Learning Classification of Cirrhotic Patients with and without Minimal Hepatic Encephalopathy Based on Regional Homogeneity of Intrinsic Brain Activity. [PDF]

open access: yesPLoS ONE, 2016
Machine learning-based approaches play an important role in examining functional magnetic resonance imaging (fMRI) data in a multivariate manner and extracting features predictive of group membership.
Qiu-Feng Chen   +4 more
doaj   +1 more source

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