Results 111 to 120 of about 15,308,393 (377)
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Exploring the Association of Helicobacter pylori With Anti-intrinsic Factor and Anti-parietal Cell Antibodies in Pernicious Anemia: A Systematic Review. [PDF]
Allakky A.
europepmc +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Cathepsin B Is Not an Intrinsic Factor Related to Asparaginase Resistance of the Acute Lymphoblastic Leukemia REH Cell Line. [PDF]
Costa IM +7 more
europepmc +1 more source
This research is aimed to identify intrinsic and extrinsic motivation of graduate students in English Education Master Program batch 2018. However, motivation became the most dominant factor to build in relation to the academic performance.
Elizabeth Elizabeth, Ouda Teda Ena
doaj +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Line selection method with transient state based on intrinsic mode energy
In view of problem that fault line selection method based on wavelet analysis of coal mine power grid ca't guarantee the optimal decomposition effect due to the decomposition effect depends on choice of primary function, the paper presented a fault line ...
WANG Qing-liang +4 more
doaj +1 more source
Using a spectral analysis of bright Chandra X-ray sources located in 27 nearby galaxies and maps of star-formation rate (SFR) and ISM surface densities for these galaxies, we constructed the intrinsic X-ray luminosity function (XLF) of luminous high-mass
Khabibullin, Ildar, Sazonov, Sergey
core +1 more source
Intrinsic biological activity of the thrombospondin structural homology repeat in connective tissue growth factor [PDF]
Zhen-yue Tong, David R. Brigstock
openalex +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source

