Results 151 to 160 of about 15,218,319 (382)

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

foxl3 is a germ cell–intrinsic factor involved in sperm-egg fate decision in medaka

open access: yesScience, 2015
T. Nishimura   +7 more
semanticscholar   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Permittivity-asymmetric chiral metasurfaces empowered by bound states in the continuum

open access: yesFrontiers in Physics
The intrinsic chirality of natural materials is usually weak or absent. To enlarge circular dichroism, chiral metasurfaces supporting bound states in the continuum have been widely investigated.
Yang Li   +5 more
doaj   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

How Gamification Enhances Learning Effectiveness Through Blended Learning and Intrinsic Motivation: The Moderating Effects of Self-Regulation

open access: yesSAGE Open
This study set out to examine how the features of gamification (immersion, achievement, and social interaction) affect intrinsic motivation, ultimately enhancing student learning effectiveness in blended learning.
Bang Nguyen-Viet, Huong Doan Ngoc Minh
doaj   +1 more source

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