Results 11 to 20 of about 1,784,092 (240)

Intrinsic Immune Mechanisms Restricting Human Cytomegalovirus Replication

open access: yesViruses, 2021
Cellular restriction factors (RFs) act as important constitutive innate immune barriers against viruses. In 2006, the promyelocytic leukemia protein was described as the first RF against human cytomegalovirus (HCMV) infection which is antagonized by the ...
Eva-Maria Schilling   +2 more
doaj   +1 more source

A High Power Factor LED Driver with Intrinsic Current Balancing Capability

open access: yesApplied Sciences, 2023
The research proposed a novel LED driver with the functions of power-factor correction (PFC) and current balancing. A flyback converter and a Class-D series resonant converter were integrated by sharing an active switch to form a single-stage circuit ...
Hung-Liang Cheng, Yi-Chan Hung
doaj   +1 more source

What do we know about hallux valgus pathogenesis?

open access: yesJournal of the Foot & Ankle, 2020
Objective: This work performs a critical review of the different causes described to explain the etiopathogenesis of hallux valgus. Methods: The authors divide the causal factors into two groups: extrinsic and intrinsic factors.
Martín Ferreyra   +5 more
doaj   +1 more source

The transcription factor Pou3f1 promotes neural fate commitment via activation of neural lineage genes and inhibition of external signaling pathways

open access: yeseLife, 2014
The neural fate commitment of pluripotent stem cells requires the repression of extrinsic inhibitory signals and the activation of intrinsic positive transcription factors.
Qingqing Zhu   +13 more
doaj   +1 more source

Human gut Bacteroides capture vitamin B12 via cell surface-exposed lipoproteins

open access: yeseLife, 2018
Human gut Bacteroides use surface-exposed lipoproteins to bind and metabolize complex polysaccharides. Although vitamins and other nutrients are also essential for commensal fitness, much less is known about how commensal bacteria compete with each other
Aaron G Wexler   +5 more
doaj   +1 more source

Genome-Wide CRISPR-Cas9 Screen Identifies SMCHD1 as a Restriction Factor for Herpesviruses

open access: yesmBio, 2023
Intrinsic immunity is the frontline of host defense against invading pathogens. To combat viral infection, mammalian hosts deploy cell-intrinsic effectors to block viral replication prior to the onset of innate and adaptive immunity.
Xuezhang Tian   +15 more
doaj   +1 more source

Latent functional connectivity underlying multiple brain states

open access: yesNetwork Neuroscience, 2022
Functional connectivity (FC) studies have predominantly focused on resting state, where ongoing dynamics are thought to reflect the brain’s intrinsic network architecture; thought to be broadly relevant because it persists across brain states (i.e ...
Ethan M. McCormick   +4 more
doaj   +1 more source

THE INFLUENCE OF INTRINSIC AND EXTRINSIC FACTOR ON COMMITMENT AND THE IMPACT ON THE PERFORMANCE OF EMPLOYEES

open access: yesManajemen dan Bisnis, 2015
This study aimed to determine the influence of intrinsic and extrinsic factors on commitment and impact on the performance of employees of Sejahtera Sunindo Trada Company.
Tri Bodroastuti, Aprillia Putri Andhani
doaj   +1 more source

Evaluating intrinsic and non-intrinsic cancer risk factors [PDF]

open access: yesNature Communications, 2018
AbstractDiscriminating the contribution of unmodifiable random intrinsic DNA replication errors (‘bad luck’) to cancer development from those of other factors is critical for understanding cancer in humans and for directing public resources aimed at reducing the burden of cancer.
Song Wu   +3 more
openaire   +4 more sources

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