Results 101 to 110 of about 858,701 (293)

Faults Diagnostics of Railway Axle Bearings Based on IMF’s Confidence Index Algorithm for Ensemble EMD

Sensors, 2015
As train loads and travel speeds have increased over time, railway axle bearings have become critical elements which require more efficient non-destructive inspection and fault diagnostics methods. This paper presents a novel and adaptive procedure based
Cai Yi, Jianhui Lin, Weihua Zhang, Jianming Ding   +3 more
doaj   +1 more source

High resolution kinematics of galactic globular clusters. II. On the significance of velocity dispersion measurements [PDF]

, 1993
Small number statistics may heavily affect the structure of the broadening function in integrated spectra of galactic globular cluster centers. As a consequence, it is a priori unknown how closely line broadening measure- ments gauge the intrinsic ...
Capaccioli, Massimo, Piotto, Giampaolo, Zaggia, Simone R.   +2 more
core   +2 more sources

The source-lens clustering effect in the context of lensing tomography and its self-calibration

, 2015
Cosmic shear can only be measured where there are galaxies. This source-lens clustering (SLC) effect has two sources, intrinsic source clustering and cosmic magnification (magnification/size bias). Lensing tomography can suppress the former.
Cui, Weiguang, Lin, Weipeng, Yu, Yu, Zhang, Pengjie   +3 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Material limitations of carbon-nanotube inertial balances: on the possibility of intrinsic yoctogram mass resolution at room temperature

, 2010
We present a theoretical study of the intrinsic quality factor of the fundamental flexural vibration in a carbon nanotube and its dependence on temperature, radius, length and tension.
Arias, T. A., Lischner, Johannes
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

A Hybrid Model Combining Signal Decomposition and Inverted Transformer for Accurate Power Transformer Load Prediction

Applied Sciences
Transformer load is a key factor influencing its aging and service life. Accurately predicting load trends is crucial for assisting load redistribution.
Shuguo Gao, Chenmeng Xiang, Yanhao Zhou, Haoyu Liu, Lujian Dai, Tianyue Zhang, Yi Yin   +6 more
doaj   +1 more source

Estimation the wear state of milling tools using a combined ensemble empirical mode decomposition and support vector machine method

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2018
Vibrational signals resulting from tool wear have non-linear and non-stationary features. It is also difficult to acquire large numbers of typically worn samples in practice.
Chuangwen XU, Yuzhen CHAI, Huaiyuan LI, Zhicheng SHI   +3 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source