Results 81 to 90 of about 215,660 (296)

A Method for Determining Intrinsic Mode Function Number in Variational Mode Decomposition and Its Application to Bearing Vibration Signal Processing

open access: yes, 2020
Variational mode decomposition (VMD) method has been widely used in the field of signal processing with significant advantages over other decomposition methods in eliminating modal aliasing and noise robustness.
Junzhen Zhu   +4 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Line selection method with transient state based on intrinsic mode energy

open access: yesGong-kuang zidonghua, 2013
In view of problem that fault line selection method based on wavelet analysis of coal mine power grid ca't guarantee the optimal decomposition effect due to the decomposition effect depends on choice of primary function, the paper presented a fault line ...
WANG Qing-liang   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Measurement and Analysis of Current Signals for Gearbox Fault Recognition of Wind Turbine

open access: yesMeasurement Science Review, 2013
This paper presents a novel solution method based on measurement and analysis of current signals for gearbox fault recognition of wind turbine. A gearbox with typical oil-leakage fault is purposely made.
Lin Deng-Fa, Chen Po-Hung, Williams Mike
doaj   +1 more source

Fault diagnosis of rolling bearings based on variational mode decomposition and calculus enhanced energy operator

open access: yes工程科学学报, 2016
Aiming at the characteristics of rolling bearing fault vibration signals and considering the merits of variational mode decomposition in mono-component separation and calculus enhanced energy operator in transient impulse detection, this article ...
ZHANG Dong, FENG Zhi-peng
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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