Results 71 to 80 of about 215,660 (296)

RESEARCH ON FAULT DIAGNOSIS METHOD OF ROLLING BEAR BASED ON SYMBOLIC ANALYSIS OF INTRINSIC MODE FUNCTION

open access: yes, 2016
A fault diagnosis method of the intrinsic mode components symbolic analysis is proposed on the basis of empirical mode decomposition. Firstly,the extension fault signal is decomposed into several intrinsic mode functions under different time scales with ...
HOU HePing, LIU Kai, XU ZhuoFei
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Intrinsic coupling modes reveal the functional architecture of cortico-tectal networks [PDF]

open access: yesScience Advances, 2015
Summary In the absence of sensory stimulation or motor output, the brain exhibits complex spatiotemporal patterns of intrinsically generated neural activity. However, little is known about how such patterns of activity are correlated between cortical and subcortical brain areas. Here, we investigate the large-scale correlation structure
Stitt, Iain   +6 more
openaire   +3 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Compound Fault Diagnosis for Gearbox based on Variational ModeDecomposition and Correlated Kurtosis

open access: yesJixie chuandong, 2019
Aiming at the characteristics of non-linear, non-stationary, multi-noise and multi-fault signals of the compound fault signal in gearboxes, a compound fault diagnosis method for gearboxes based on variational mode decomposition and correlated kurtosis is
Zhang Xin   +4 more
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Development of a normal mode-based geometric simulation approach for investigating the intrinsic mobility of proteins

open access: yes, 2010
Specific functions of biological systems often require conformational transitions of macromolecules. Thus, being able to describe and predict conformational changes of biological macromolecules is not only important for understanding their impact on ...
Ahmed, Aqeel
core  

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Residue feature analysis with empirical mode decomposition for mining spatial sequential patterns from serial remote sensing images

open access: yesНаучно-технический вестник информационных технологий, механики и оптики
An extensive growth of serial remote sensing images paves the way for abundant data intended for the sequential spatial pattern determination in several fields like monitoring of agriculture, development of urban areas, and the vegetative area.
R. A. Preethi, G. Anandharaj
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

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