Results 121 to 130 of about 15,642,647 (329)

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Angajamentul studenților față de interesul public. Fundamentul unui serviciu public orientat spre cetățean

Revista Transilvană de Ştiinţe Administrative
Public Service Motivation (PSM) has emerged as a pivotal framework for understanding the intrin­sic drivers that inspire individuals to pursue careers in the public sector.
Simona Claudia Creța, Raluca Ioana Antonie   +1 more
doaj  

Reference values for handgrip strength and their association with intrinsic capacity domains among older adults

Journal of Cachexia, Sarcopenia and Muscle, 2019
Objective The purposes of this study were three‐fold: (i) to describe handgrip strength in older individuals aged ≥60 years in Colombia; (ii) to identify sex‐specific and age‐specific muscle weakness cut‐off points in older adults; and (iii) to determine
Robinson Ramírez‐Vélez, Jorge Enrique Correa‐Bautista, Antonio García‐Hermoso, Carlos Alberto Cano, Mikel Izquierdo   +4 more
doaj   +1 more source

Bitcoin intrinsic value

, 2022
Next I will assess the current health of the asset on the basis of its own fundamentals. You can go to the “tldr” summary at the end if you want to skip straight to my conclusions on price predictions. (Disclaimer: This is not financial advice, make sure to always do your own research).
openaire   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

How Transformational Leadership, Corporate Culture, and Intrinsic Motivation Shape Hospitality Employee Performance?

Jurnal Manajemen Teori dan Terapan
Objective: Guided by Self-Determination Theory (SDT), this study investigates the effects of transformational leadership, corporate culture, and company values on intrinsic motivation and employee performance in the hospitality industry. Design/Methods/
Mohamad Yusak Anshori, Reizano Amri Rasyid, Teguh Herlambang   +2 more
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Unravelling nature's values in EU agricultural policy: A critical discourse analysis

People and Nature
Agriculture plays a dual role as both a key driver and a potential solution for biodiversity loss. Farmers, holding a variety of values related to nature, are therefore key actors in biodiversity conservation.
Iven Froese, Lasse Loft
doaj   +1 more source