Results 61 to 70 of about 720,430 (259)
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Age-specific growth, reproductive values, and intrinsic r
Demographic Research, 2011 The age-specific growth function of an observed population and the reproductive value function based on the population's current vital rates determine the intrinsic rate of growth implied by those vital rates through the simple relationship given in
Robert Schoen
doaj
The interplay of work values, job satisfaction and intention to stay among millennials in Indonesia
Cogent Business & ManagementThis study aims to investigate the relationship between work values (intrinsic and extrinsic), job satisfaction and intention to stay among millennial employees in Indonesia.
Yuniadi Mayowan +3 more
doaj +1 more source
"I Climbed a Fig Tree, on an Apple Bashing Spree, Only Pears Fell Free": Economic, Symbolic and Intrinsic Values of Plants Occurring in Slovenian Folk Songs Collected by K. Štrekelj (1895-1912). [PDF]
Plants (Basel), 2022 Fišer Ž.
europepmc +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
English Community Journal, 2017 The objectives of this research were to find out the intrinsic elements and the moral values in Totto Chan: the Little Girl at the Window novel. This research employed descriptive qualitative as the method.
Ardayati Ardayati, Asih Rahayu
doaj
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source