The “Intrinsic Value” of Cultural Heritage as Driver for Circular Human-Centered Adaptive Reuse
By referring to the European Green Deal, this paper analyzes the “intrinsic value” of cultural heritage by investigating the human-centered adaptive reuse of this heritage.
L. F. Girard, M. Vecco
semanticscholar +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Dissipationless Spin Current in Anisotropic p-Doped Semiconductors
Recently, dissipationless spin current has been predicted for the p-doped semiconductors with spin-orbit coupling. Here we investigate the effect of spherical symmetry breaking on the dissipationless spin current, and obtain values of the intrinsic spin ...
Bogdan A. Bernevig +4 more
core +1 more source
Chandra Observations of 3C Radio Sources with z<0.3: Nuclei, Diffuse Emission, Jets and Hotspots [PDF]
We report on our Chandra Cycle 9 program to observe half of the 60 (unobserved by Chandra) 3C radio sources at ...
A. Capetti +46 more
core +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Radiationless travelling waves in saturable nonlinear Schrödinger lattices [PDF]
The longstanding problem of moving discrete breathers (intrinsic localised modes) in nonlinear Schrödinger lattices is revisited. The context is photorefractive crystal lattices with saturable nonlinearity whose generalised Peierls-Nabarro barrier ...
Champneys, AR +3 more
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Pharmacists' perceptions of pharmacy technician occupational values
Background: Pharmacy technician scope of practice has expanded in recent years to attempt to alleviate the responsibility burden placed on pharmacists in some states. However, little research has examined the ways in which pharmacists attempt to persuade
Wesley Sparkmon +6 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source

