Results 191 to 200 of about 448,472 (368)

Rejuvenation of CcdB-Poisoned Gyrase by an Intrinsically Disordered Protein Domain [PDF]

, 2009
Natalie De Jonge, Abel Garcia‐Pino, L. Buts, Sarah Haesaerts, Daniël Charlier, Klaus Zangger, Lode Wyns, Henri De Greve, Remy Loris   +8 more
openalex   +1 more source

Physics-based computational and theoretical approaches to intrinsically disordered proteins.

Current Opinion in Structural Biology, 2021
J. Shea, R. Best, J. Mittal
semanticscholar   +1 more source

Intrinsically Soft Implantable Electronics for Long‐term Biosensing Applications

Advanced Sensor Research, EarlyView.
Intrinsically soft implantable biosensors address the mechanical mismatch of conventional rigid implants, improving biocompatibility and stability. This review explores soft encapsulation matrices, stretchable conductors, implantation strategies, and chronic fixation techniques.
Su Hyeon Lee, Hyo Jin Lee, Sohye Lee, Dae‐Hyeong Kim, Hye Jin Kim, Sung‐Hyuk Sunwoo   +5 more
wiley   +1 more source

Intrinsic disorder in the C-terminal domain of the Shaker voltage-activated K ⁺ channel modulates its interaction with scaffold proteins

, 2007
Elhanan Magidovich, Irit Orr, Deborah Fass, Uri Abdu, Ofer Yifrach   +4 more
openalex   +1 more source

Toward a quantitative theory of intrinsically disordered proteins and their function [PDF]

, 2009
Jintao Liu, James R. Faeder, Carlos J. Camacho   +2 more
openalex   +1 more source

Opportunities in Therapeutic mRNA Stabilization: Sequence, Structure, Adjuvants and Vectors

Advanced Therapeutics, EarlyView.
Current mRNA lipid nanoparticles rely on cold storage, which increases the cost and reduces access to the vaccines. As mRNA expands to other clinical opportunities, better methods to stabilize the medicines during shipping, storage, and delivery are needed.
Joshua A. Choe, Jacobus Burger, Jamie Jones, Apurva Panjla, William L. Murphy   +4 more
wiley   +1 more source

S12A3 NMR dynamics and intrinsically disordered state of transcription-related proteins(Unifying Comprehension from Genome to Cells through Reconsideration of Protein)

, 2007
Yoshifumi Nishimura
openalex   +2 more sources

Analysis of structured and intrinsically disordered regions of transmembrane proteins [PDF]

, 2009
Bin Xue, Liwei Li, Samy O. Meroueh, Vladimir N. Uversky, A. Keith Dunker   +4 more
openalex   +1 more source

Immune Checkpoint PD‐L1 Modulates Retinal Microglial Activation to Alleviate Vascular Leakage in Choroidal Neovascularization via ERK

Advanced Science, EarlyView.
PD‐L1 limits neuroinflammation in neovascular AMD by modulating microglial activation. Its deficiency exacerbates vascular leakage and choroidal neovascularization (CNV) via ERK signaling, while enhancing PD‐L1 reduces inflammation and neovascularization. Targeting PD‐L1 may offer a novel immunomodulatory strategy for NVAMD.
Yue Zou, Junliang Jiang, Yunqin Li, Xinyi Ding, Qiuping Tong, Ying Shi, Lei Xiao, Ling Chen   +7 more
wiley   +1 more source

IDP-Bert: Predicting Properties of Intrinsically Disordered Proteins (IDP) Using Large Language Models [PDF]

arXiv
Intrinsically Disordered Proteins (IDPs) constitute a large and structure-less class of proteins with significant functions. The existence of IDPs challenges the conventional notion that the biological functions of proteins rely on their three-dimensional structures.
arxiv