Results 211 to 220 of about 1,883,575 (282)

Accurate Generation of Conformational Ensembles for Intrinsically Disordered Proteins with IDPFold. [PDF]

Adv Sci (Weinh)
Zhu J, Li Z, Zheng Z, Zhang B, Zhong B, Bai J, Hong X, Wang T, Wei T, Yang J, Chen HF.   +10 more
europepmc   +1 more source

Determining accurate conformational ensembles of intrinsically disordered proteins at atomic resolution [PDF]

Struct Dyn
Borthakur K, Sisk T, Panei F, Bonomi M, Robustelli P.   +4 more
europepmc   +2 more sources

Diffusing protein binders to intrinsically disordered proteins. [PDF]

Nature
Liu C, Wu K, Choi H, Han HL, Zhang X, Watson JL, Ahn G, Zhang JZ, Shijo S, Good LL, Fischer CM, Bera AK, Kang A, Brackenbrough E, Coventry B, Hick DR, Qamar S, Li X, Decarreau J, Gerben SR, Yang W, Goreshnik I, Vafeados D, Wang X, Lamb M, Murray A, Kenny S, Bauer MS, Hoofnagle AN, Zhu P, Knowles TPJ, Baker D.   +31 more
europepmc   +1 more source

Heat‐Suppressing Projection Two‐Photon Lithography Enables High‐Throughput Sub‐Micrometer Manufacturing of Biopolymer Hydrogels for Tissue Engineering

Advanced Science, EarlyView.
The iLEAP technique integrates high‐throughput two‐photon lithography with extrusion printing, bridging sub‐micrometer precision and macroscopic scaffold fabrication. By employing a low‐exothermic photoinitiator, it mitigates thermal damage to biopolymers and preserves bioactivity.
Qifeng Guan, Yanzhe Fu, Xiangyu Xu, Naitao Li, Sen Hou, Kai Wang, Yufan Wang, Jiakun Li, Ping Li, Jiebo Li, Lizhen Wang, Yubo Fan   +11 more
wiley   +1 more source

New Approach for Targeting Small-Molecule Candidates for Intrinsically Disordered Proteins. [PDF]

Methods Protoc
Senćanski M.
europepmc   +1 more source

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

Advanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia, Haojie Wu, Xingyun Li, Lining Liu, Kaiqing Song, Jinpei Cui, Jie Liu, Jiaxuan Yin, Emtiaz Ahmed, Yusuke Yamauchi, Xue Li   +10 more
wiley   +1 more source

Single-Molecule Techniques for Probing the Conformation, Dynamics and Interactions of Intrinsically Disordered Proteins. [PDF]

Biophys Rev (Melville)
DeCoeur D, Chen M, Chen J.
europepmc   +1 more source

Multimodal Bioinspired Self‐Healing Composites Enabling Durable and High‐Efficiency Wearable Perovskite Light‐Emitting Diodes

Advanced Science, EarlyView.
Butterfly wing–inspired intrinsically self‐healing polymer interlayers enable flexible perovskite optoelectronics with high luminance, strain‐insensitive stability, and environmental resilience. These hierarchically structured films redistribute mechanical stress, suppress defect formation, and maintain performance under repeated bending, paving the ...
Loganathan Veeramuthu, Yu‐Chen Wang, Chun‐Tse Tsai, Yen‐Lin Tseng, Xuan Ting King, Tzu‐Ming Hsu, Zhen‐Li Yan, Fang‐Cheng Liang, Pei‐Yin Chen, Georgy Dosovitskiy, Yehonadav Bekenstein, Hyunjin Lee, Tao Zhou, Chi‐Ching Kuo   +13 more
wiley   +1 more source

Biochemically Constrained Multi‐Omics Integration Reveals Protein–Metabolite Dependencies Across Diseases

Advanced Science, EarlyView.
ProMetNet introduces a biologically constrained deep learning framework for proteo‐metabolomic integration by embedding Reactome‐derived pathway topology into neural networks. It captures non‐linear molecular dependencies and pathway‐level metabolic reorganization, enabling interpretable discrimination.
Minghui Zhao, Na Zhou, Ruotong Liu, Xiaofei Li, Jian Li, Fuzhong Xue, Qingzhen Hou   +6 more
wiley   +1 more source

Characterizing Structural and Kinetic Ensembles of Intrinsically Disordered Proteins Using Writhe. [PDF]

J Chem Theory Comput
Sisk TR, Olsson S, Robustelli P.
europepmc   +1 more source