Intrinsic disorder in scaffold proteins: Getting more from less
Marc S. Cortese+2 more
openalex +1 more source
Large-scale Analysis of Thermo-stable, Mammalian Proteins Provides Insights into the Intrinsically Disordered Proteome [PDF]
Charles A. Galea+11 more
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Noise‐induced synaptopathy (NIS) is largely reversible due to self‐repair. NIS and noise‐induced hidden hearing loss are two concepts with similarities and differences. The major hearing deficits in NIHHL are temporal processing disorders. The translation of animal data in NIS studies to humans is hindered by many factors.
Hui Wang, Steven J Aiken, Jian Wang
wiley +1 more source
Targeting intrinsically disordered proteins in neurodegenerative and protein dysfunction diseases: another illustration of the D2concept [PDF]
Vladimir N. Uversky
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Electrical Microneedles for Wound Treatment
A review on state‐of‐art research concerning electrical microneedles applied for wound treatment is presented. After a comprehensive analysis of mechanisms of electrical stimulation on wound healing, the derived three types of electrical microneedles are clarified and summarized. Further, their applications in wound healing are highlighted.
Yu Wang+6 more
wiley +1 more source
Computational Methods to Investigate Intrinsically Disordered Proteins and their Complexes [PDF]
In 1999 Wright and Dyson highlighted the fact that large sections of the proteome of all organisms are comprised of protein sequences that lack globular folded structures under physiological conditions. Since then the biophysics community has made significant strides in unraveling the intricate structural and dynamic characteristics of intrinsically ...
arxiv
Vital for Viruses: Intrinsically Disordered Proteins. [PDF]
Dyson HJ.
europepmc +1 more source
Structural Diversity in Free and Bound States of Intrinsically Disordered Protein Phosphatase 1 Regulators [PDF]
Joseph A. Marsh+5 more
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Nanotherapy for Neural Retinal Regeneration
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu+11 more
wiley +1 more source
Cryoprotective mechanism of a small intrinsically disordered dehydrin protein [PDF]
Stephanie L. Hughes, Steffen P. Graether
openalex +1 more source