Implantable Self‐Powered Systems for Electrical Stimulation Medical Devices
Advanced Science, EarlyView.In this paper, the design strategy and clinical application of ISS are discussed in depth from four aspects: the design and optimization of the energy collection module, the selection and preparation of adaptive electrode materials, the innovation of system design strategy, and the biological effect of electrical stimulation of ISS.
Xi Cui, Li Wu, Chao Zhang, Zhou Li
wiley +1 more source
The Origin of Discrepancies between Predictions and Annotations in Intrinsically Disordered Proteins. [PDF]
Biomolecules, 2023 Pajkos M, Erdős G, Dosztányi Z.
europepmc +1 more source
High Fat Low Carbohydrate Diet Is Linked to CNS Autoimmunity Protection
Advanced Science, EarlyView.Mapping global epidemiological data to macronutrient supply reveals high carbohydrate, in contrast to high fat supply, associates with increased multiple sclerosis (MS) prevalence and incidence. This is confirmed in a mouse MS model, experimental autoimmune encephalomyelitis (EAE), using isocaloric diets: a high carbohydrate diet aggravates, a high ...
Duan Ni +15 more
wiley +1 more source
Effects of Macromolecular Crowding on an Intrinsically Disordered Protein Characterized by Small-Angle Neutron Scattering with Contrast Matching [PDF]
, 2011 Daniel Johansen +4 more
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IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation
Advanced Science, EarlyView.LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.
Jiena Liu +10 more
wiley +1 more source
Atomistic Ensemble Modeling and Small-Angle Neutron Scattering of Intrinsically Disordered Protein Complexes: Applied to Minichromosome Maintenance Protein [PDF]
, 2011 Susan Krueger +4 more
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Advanced Science, EarlyView.This study reveals histone lactylation as a metabolic‐epigenetic regulator countering cellular senescence and skeletal muscle aging. Reduced lactylation impairs cell cycle, DNA repair and proteostasis pathways, while exercise restores glycolytic activity and lactylation levels, preserving muscle function.
Fanju Meng +16 more
wiley +1 more source
Successful prediction of LC8 binding to intrinsically disordered proteins sheds light on AlphaFold's black box. [PDF]
Front Mol BiosciWalker DR +3 more
europepmc +1 more source
From Immunogenic Peptides to Intrinsically Disordered Proteins. [PDF]
Isr J Chem, 2023 Dyson HJ, Wright PE.
europepmc +1 more source
The IntFOLD server: an integrated web resource for protein fold recognition, 3D model quality assessment, intrinsic disorder prediction, domain prediction and ligand binding site prediction [PDF]
, 2011 Daniel B. Roche +3 more
openalex +1 more source