Results 241 to 250 of about 448,472 (368)

Landscape of intrinsically disordered proteins in mental disorder diseases. [PDF]

open access: yesComput Struct Biotechnol J
Zhang X   +8 more
europepmc   +1 more source

Binary classification of protein molecules into intrinsically disordered and ordered segments [PDF]

open access: hybrid, 2011
Satoshi Fukuchi   +4 more
openalex   +1 more source

Structure, Mechanics, and Mechanobiology of Fibrocartilage Pericellular Matrix Mediated by Type V Collagen

open access: yesAdvanced Science, EarlyView.
This study defines the structure, mechanics, and mechanobiology of the fibrocartilage pericellular matrix (PCM) using the murine meniscus, showing how collagen V deficiency alters PCM properties and disrupts cell mechanosensitive signaling. Findings emphasize the critical role of PCM in fibrocartilage mechanobiology and suggest targeting it can enhance
Chao Wang   +13 more
wiley   +1 more source

Using temperature coefficients to support resonance assignment of intrinsically disordered proteins. [PDF]

open access: yesJ Biomol NMR
Putko P   +5 more
europepmc   +1 more source

The ins and outs of membrane bending by intrinsically disordered proteins. [PDF]

open access: yesSci Adv, 2023
Yuan F   +7 more
europepmc   +1 more source

Unraveling Neurodevelopment: Synergistic Effects of Intrinsic Genetic Programs and Extrinsic Environmental Cues

open access: yesAdvanced Science, EarlyView.
Overview of the regulation of intrinsic and extrinsic signals during neurodevelopment. Intrinsic genetic signals from NSCs, in conjunction with cues from microglia and blood vessels, collaboratively regulate the proliferation of NSCs, their fate determination, synaptogenesis, synaptic pruning, neuronal survival, and death, as well as communication ...
Yanyan Wang   +4 more
wiley   +1 more source

MOBIDB in 2025: integrating ensemble properties and function annotations for intrinsically disordered proteins. [PDF]

open access: yesNucleic Acids Res
Piovesan D   +8 more
europepmc   +1 more source

PSMD14 Stabilizes SLC7A11 to Ameliorate Glucocorticoid‐Induced Osteoporosis by Suppressing Osteocyte Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glucocorticoid‐induced osteoporosis (GIOP) triggers osteocyte ferroptosis via SLC7A11 degradation. PSMD14 stabilizes SLC7A11 by counteracting glucocorticoid‐driven ubiquitination, preserving cystine uptake and glutathione synthesis. AAV‐mediated PSMD14 delivery or its agonist Pantethine rescues osteocyte survival and bone loss in GIOP mice.
Yifeng Shi   +20 more
wiley   +1 more source

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