Results 61 to 70 of about 2,551 (127)

Molecular and Cellular Underpinnings of Primary Hypertension: An Integrative Mechanistic Framework

Journal of Cellular Physiology, Volume 241, Issue 10, October 2026.
ABSTRACT Hypertension is a highly prevalent clinical condition and a major contributor to global cardiovascular morbidity and mortality. Despite extensive research, its complex and multifaceted pathogenesis is yet to be fully elucidated. This paper explores the updated understanding of primary hypertension as a systemic disorder rather than an isolated
Dima Nasrallah, Alaa Abdelhamid, Omar Tluli, Yaman Al‐Haneedi, Mera Abu Hussien, Ali H. Eid   +5 more
wiley   +1 more source

Melanopsin‐Mediated Post‐Illumination Pupillary Response in Idiopathic Rapid Eye Movement (REM) Sleep Behavior Disorder and Parkinson's Disease

Movement Disorders, Volume 41, Issue 10, Page 2706-2711, October 2026.
Abstract Aims To conduct a case–control study to investigate melanopsin‐mediated post‐illumination pupillary response (PIPR) in patients with Parkinson's disease (PD), video‐polysomnography‐confirmed isolated/idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD), and age‐matched healthy controls (HC). Methods PIPR was measured at 6 s after
Joey W.Y. Chan, Bei Huang, Siyi Gong, Yuhua Yang, Shi Tang, Steven Wai‐ho Chau, Ngan Yin Chan, Tim Man‐ho Li, Yaping Liu, Anne Y.Y. Chan, Karen K.Y. Ma, Shirley X. Li, Joshua Tsoh, Kelvin K.L. Chong, Kathryn A. Roecklein, Vincent C.T. Mok, Yun Kwok Wing   +16 more
wiley   +1 more source

Blue Light Exposure During Sleep in Type 1 Diabetes: Impacts on Glycemic Control and Psychosocial Health

Journal of Sleep Research, Volume 35, Issue 5, October 2026.
ABSTRACT Light exposure at night is linked to increased risk for obesity and insulin resistance in the general population. While sleep health is recognized as a key component of diabetes management, there has been less emphasis on nighttime light exposure. This study aimed to investigate the effects of blue and white light exposure immediately prior to
Seok Jin Hong, Sarida Pratuangtham, Pamela Martyn‐Nemeth, Alana D. Steffen, Chang Gi Park, Sirimon Reutrakul   +5 more
wiley   +1 more source

Hybrid Flexible–Soft Neural Interface as a Practical Solution for Long‐Term Implants

Rare Metals, Volume 45, Issue 9, September 2026.
ABSTRACT Implantable neural interfaces face persistent challenges in long‐term functionality due to chronic immune responses, mechanical mismatch with tissue, and material corrosion in vivo. The commonly used flexible materials, such as polyimide and parylene‐C (poly[monochloro‐p‐xylylene]), have advantages in low water vapor permeability and high ...
Bowen Ji, Zimo Zhang, Xiaoli You, Xuanqi Wang, Ye Huang, Jiaxu Cao, Ruiyu Bai, Jun Chen, Haitao Zhao, Honglong Chang, Sergey Antonovich Chizhik, Yuri Mikhailovich Kernasovsky, Huiling Peng, Minghao Wang   +13 more
wiley   +1 more source

Cellular properties of intrinsically photosensitive retinal ganglion cells during postnatal development

Neural Development, 2019
Background Melanopsin-expressing, intrinsically photosensitive retinal ganglion cells (ipRGCs) respond directly to light and have been shown to mediate a broad variety of visual behaviors in adult animals.
Jasmine A. Lucas, Tiffany M. Schmidt
doaj   +1 more source

Melanopsin-Mediated Acute Light Responses Measured in Winter and in Summer: Seasonal Variations in Adults with and without Cataracts

Frontiers in Neurology, 2017
Seasonal adaptation is a ubiquitous behavior seen in many species on both global hemispheres and is conveyed by changing photoperiods. In humans this seasonal adaptation is less apparent, in part because changes in daylength are masked by the use of ...
Mirjam Münch, Myriam Ladaique, Ségolène Roemer, Kattayoon Hashemi, Aki Kawasaki   +4 more
doaj   +1 more source

Light tunes long-term threat avoidance behavior in male mice

Nature Communications
Animals must constantly scan their environment for imminent threats to their safety. However, they must also integrate their past experiences across long timescales to assess the potential recurrence of new threats.
Marcos L. Aranda, Eric Min, Lucy T. Liu, Anika E. Schipma, Hui Wang, Tiffany M. Schmidt   +5 more
doaj   +1 more source

The Method of Silent Substitution for Examining Melanopsin Contributions to Pupil Control

Frontiers in Neurology, 2018
The human pupillary light response is driven by all classes of photoreceptors in the human eye—the three classes of cones, the rods, and the intrinsically photosensitive retinal ganglion cells (ipRGCs) expressing the photopigment melanopsin.
Manuel Spitschan, Tom Woelders
doaj   +1 more source

Intrinsically photosensitive retinal ganglion cell-driven pupil responses in patients with traumatic brain injury. [PDF]

Vision Res, 2021
Mostafa J, Porter J, Queener HM, Ostrin LA.   +3 more
europepmc   +1 more source

The effect of intrinsically photosensitive retinal ganglion cell (ipRGC) stimulation on axial length changes to imposed optical defocus in young adults. [PDF]

J Optom, 2023
Chakraborty R, Collins MJ, Kricancic H, Davis B, Alonso-Caneiro D, Yi F, Baskaran K.   +6 more
europepmc   +1 more source