Results 1 to 10 of about 6,987 (212)

Phosphorylation of mouse melanopsin by protein kinase A.

PLoS ONE, 2012
The visual pigment melanopsin is expressed in intrinsically photosensitive retinal ganglion cells (ipRGCs) in the mammalian retina, where it is involved in non-image forming light responses including circadian photoentrainment, pupil constriction ...
Joseph R Blasic, R Lane Brown, Phyllis R Robinson   +2 more
doaj   +4 more sources

The multistable melanopsins of mammals

Frontiers in Ophthalmology, 2023
Melanopsin is a light-activated G protein coupled receptor that is expressed widely across phylogeny. In mammals, melanopsin is found in intrinsically photosensitive retinal ganglion cells (ipRGCs), which are especially important for “non-image” visual ...
Alan J. Emanuel, Michael Tri H. Do
doaj   +3 more sources

Human melanopsin-AAV2/8 transfection to retina transiently restores visual function in rd1 mice [PDF]

International Journal of Ophthalmology, 2016
AIM: To explore whether ectopic expression of human melanopsin can effectively and safely restore visual function in rd1 mice. METHODS: Hematoxylin-eosin staining of retinal sections from rd1 mice was used to detect the thickness of the outer nuclear ...
Ming-Ming Liu, Jia-Man Dai, Wen-Yi Liu, Cong-Jian Zhao, Bin Lin, Zheng-Qin Yin   +5 more
doaj   +3 more sources

Melanopsin-derived visual responses under light adapted conditions in the mouse dLGN.

PLoS ONE, 2015
A direct projection from melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs) reaches the primary visual thalamus (dorsal lateral geniculate nucleus; dLGN).
Katherine E Davis, Cyril G Eleftheriou, Annette E Allen, Christopher A Procyk, Robert J Lucas   +4 more
doaj   +2 more sources

Melanopsin-mediated image statistics from natural and human-made environments [PDF]

Scientific Reports
Melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs) play a critical role in regulating physiological and behavioral responses to light.
Pablo A. Barrionuevo, Francisco Diaz-Barrancas   +1 more
doaj   +2 more sources

Daylights with high melanopsin stimulation appear reddish in fovea and greenish in periphery

PLoS ONE, 2023
Melanopsin reportedly contributes to brightness and color appearance in photopic vision in addition to cone photoreceptor cells. However, the relationship between the contribution of melanopsin to color appearance and retinal location is unclear. Herein,
Hirokuni Higashi, Katsunori Okajima
doaj   +3 more sources

Melanopic stimulation does not alter psychophysical threshold sensitivity for luminance flicker

Scientific Reports, 2021
In addition to the rod and cone photoreceptors the retina contains intrinsically photosensitive retinal ganglion cells (ipRGCs). These cells express the photopigment melanopsin and are known to be involved in reflexive visual functions such as pupil ...
Joris Vincent, Edda B. Haggerty, David H. Brainard, Geoffrey K. Aguirre   +3 more
doaj   +1 more source

Distribution of mammalian-like melanopsin in cyclostome retinas exhibiting a different extent of visual functions.

PLoS ONE, 2014
Mammals contain 1 melanopsin (Opn4) gene that is expressed in a subset of retinal ganglion cells to serve as a photopigment involved in non-image-forming vision such as photoentrainment of circadian rhythms.
Lanfang Sun, Emi Kawano-Yamashita, Takashi Nagata, Hisao Tsukamoto, Yuji Furutani, Mitsumasa Koyanagi, Akihisa Terakita   +6 more
doaj   +1 more source

The role of gene duplication and unconstrained selective pressures in the melanopsin gene family evolution and vertebrate circadian rhythm regulation.

PLoS ONE, 2012
Melanopsin is a photosensitive cell protein involved in regulating circadian rhythms and other non-visual responses to light. The melanopsin gene family is represented by two paralogs, OPN4x and OPN4m, which originated through gene duplication early in ...
Rui Borges, Rui Borges, Warren E Johnson, Stephen J O'Brien, Vitor Vasconcelos, Agostinho Antunes   +5 more
doaj   +1 more source

Melanopsin Carboxy-terminus phosphorylation plasticity and bulk negative charge, not strict site specificity, achieves phototransduction deactivation.

PLoS ONE, 2020
Melanopsin is a visual pigment expressed in a small subset of ganglion cells in the mammalian retina known as intrinsically photosensitive retinal ganglion cells (ipRGCs) and is implicated in regulating non-image forming functions such as circadian ...
Juan C Valdez-Lopez, Sahil Gulati, Elelbin A Ortiz, Krzysztof Palczewski, Phyllis R Robinson   +4 more
doaj   +1 more source