Results 1 to 10 of about 4,663 (179)
The multistable melanopsins of mammals
Frontiers in Ophthalmology, 2023 Melanopsin is a light-activated G protein coupled receptor that is expressed widely across phylogeny. In mammals, melanopsin is found in intrinsically photosensitive retinal ganglion cells (ipRGCs), which are especially important for “non-image” visual ...
Alan J. Emanuel, Michael Tri H. Do
doaj +3 more sources
Melanopsin-mediated image statistics from natural and human-made environments [PDF]
Scientific ReportsMelanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs) play a critical role in regulating physiological and behavioral responses to light.
Pablo A. Barrionuevo +1 more
doaj +2 more sources
Phosphorylation of mouse melanopsin by protein kinase A.
PLoS ONE, 2012 The visual pigment melanopsin is expressed in intrinsically photosensitive retinal ganglion cells (ipRGCs) in the mammalian retina, where it is involved in non-image forming light responses including circadian photoentrainment, pupil constriction ...
Joseph R Blasic +2 more
doaj +3 more sources
Pupil responses to melanopsin-isolating stimuli as a potential diagnostic biomarker for glaucoma. [PDF]
PLoS ONEPurposeTo test whether differences in pupil responses to melanopsin-isolating spectral stimuli in glaucoma may be useful as a diagnostic biomarker.MethodsSpectral stimuli were presented to 20 glaucoma and 15 age-similar healthy control participants ...
Jonathan Denniss +3 more
doaj +2 more sources
Human melanopsin (OPN4) gene polymorphisms: a systematic review [PDF]
Frontiers in NeuroscienceThe melanopsin (OPN4) gene is crucial in visual and non-visual processes. Certain single-nucleotide polymorphisms (SNPs) of this gene have been linked to altered light sensitivity, photoentrainment, sleep disorders, and metabolic problems, which suggests
Kevin R. Lucio-Enríquez +4 more
doaj +2 more sources
Daylights with high melanopsin stimulation appear reddish in fovea and greenish in periphery
PLoS ONE, 2023 Melanopsin reportedly contributes to brightness and color appearance in photopic vision in addition to cone photoreceptor cells. However, the relationship between the contribution of melanopsin to color appearance and retinal location is unclear. Herein,
Hirokuni Higashi, Katsunori Okajima
doaj +3 more sources
Human melanopsin-AAV2/8 transfection to retina transiently restores visual function in rd1 mice [PDF]
International Journal of Ophthalmology, 2016 AIM: To explore whether ectopic expression of human melanopsin can effectively and safely restore visual function in rd1 mice. METHODS: Hematoxylin-eosin staining of retinal sections from rd1 mice was used to detect the thickness of the outer nuclear ...
Ming-Ming Liu +5 more
doaj +1 more source
Melanopic stimulation does not alter psychophysical threshold sensitivity for luminance flicker
Scientific Reports, 2021 In addition to the rod and cone photoreceptors the retina contains intrinsically photosensitive retinal ganglion cells (ipRGCs). These cells express the photopigment melanopsin and are known to be involved in reflexive visual functions such as pupil ...
Joris Vincent +3 more
doaj +1 more source
Melanopsin-derived visual responses under light adapted conditions in the mouse dLGN.
PLoS ONE, 2015 A direct projection from melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs) reaches the primary visual thalamus (dorsal lateral geniculate nucleus; dLGN).
Katherine E Davis +4 more
doaj +1 more source
PLoS ONE, 2014 Mammals contain 1 melanopsin (Opn4) gene that is expressed in a subset of retinal ganglion cells to serve as a photopigment involved in non-image-forming vision such as photoentrainment of circadian rhythms.
Lanfang Sun +6 more
doaj +1 more source