Results 21 to 30 of about 4,663 (179)
β-Arrestin-dependent deactivation of mouse melanopsin.
PLoS ONE, 2014 In mammals, the expression of the unusual visual pigment, melanopsin, is restricted to a small subset of intrinsically photosensitive retinal ganglion cells (ipRGCs), whose signaling regulate numerous non-visual functions including sleep, circadian ...
Evan G Cameron, Phyllis R Robinson
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Melanopsin: an exciting photopigment
Trends in Neurosciences, 2008 The discovery that mice lacking rods and cones are capable of regulating their circadian rhythms by light provided the conceptual framework for the discovery of an entirely new photoreceptor system within the mammalian eye. We now know that a small subset of retinal ganglion cells are directly photosensitive and utilize an opsin/vitamin A-based ...
Hankins, M, Peirson, S, Foster, R
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Melanopsin expression in the retinas of owls with different daily activity patterns
Journal of Photochemistry and Photobiology, 2022 Melanopsin is a photopigment found in a subset of retinal ganglion cells that is responsible for generating a series of responses to light in organisms, such as circadian rhythm regulation, pupillary light reflex, and body temperature control.
Maria Júlia Vilani Naman +6 more
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PLoS ONE, 2008 Non-image related responses to light, such as the synchronization of circadian rhythms to the day/night cycle, are mediated by classical rod/cone photoreceptors and by a small subset of retinal ganglion cells that are intrinsically photosensitive ...
Didem Göz +5 more
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PLoS ONE, 2010 Melanopsin photoreception plays a vital role in irradiance detection for non-image forming responses to light. However, little is known about the involvement of melanopsin in emotional processing of luminance.
Ma'ayan Semo +8 more
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A Review of Silent Substitution Devices for Melanopsin Stimulation in Humans
Photonics, 2020 One way to study the specific response of the non-visual melanopsin photoreceptors of the human eye is to silence the response of cones and rods. Melanopsin photoreceptors (ipRGC), highlighted in the early 2000s, are intimately linked to the circadian ...
Vincent Conus, Martial Geiser
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BMC Biology, 2023 Background The mammalian retina contains an autonomous circadian clock that controls various aspects of retinal physiology and function, including dopamine (DA) release by amacrine cells. This neurotransmitter plays a critical role in retina development,
Chaimaa Kinane +6 more
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PLoS ONE, 2015 Phosphorylation is a primary modulator of mammalian G-protein coupled receptor (GPCR) activity. The GPCR melanopsin is the photopigment of intrinsically photosensitive retinal ganglion cells (ipRGCs) in the mammalian retina. Recent evidence from in vitro
Timothy J Sexton, Russell N Van Gelder
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Melanopsin: An opsin in melanophores, brain, and eye [PDF]
Proceedings of the National Academy of Sciences, 1998 We have identified an opsin, melanopsin, in photosensitive dermal melanophores of Xenopus laevis . Its deduced amino acid sequence shares greatest homology with cephalopod opsins. The predicted secondary structure of melanopsin indicates the presence of a long cytoplasmic tail with multiple putative phosphorylation ...
Provencio, I. +4 more
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Characterization of the melanopsin gene (Opn4x) of diurnal and nocturnal snakes
BMC Evolutionary Biology, 2019 Background A number of non-visual responses to light in vertebrates, such as circadian rhythm control and pupillary light reflex, are mediated by melanopsins, G-protein coupled membrane receptors, conjugated to a retinal chromophore.
Einat Hauzman +3 more
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