Results 21 to 30 of about 6,987 (212)
Melanopsin expression in the cornea [PDF]
AbstractA unique class of intrinsically photosensitive retinal ganglion cells in mammalian retinae has been recently discovered and characterized. These neurons can generate visual signals in the absence of inputs from rods and cones, the conventional photoreceptors in the visual system. These light sensitive ganglion cells (mRGCs) express the non-rod,
Delwig, Anton +11 more
openaire +6 more sources
Melanopsin: The Tale of the Tail [PDF]
In this issue of Neuron, Mure et al. (2016) demonstrate that two mechanisms-phosphorylation of a C-terminal intracellular region, and mechanism involving the whole of the C terminus-oppositely shape the kinetics and sensitivity of the nonvisual photoreceptor melanopsin.
Russell N, Van Gelder, Ethan D, Buhr
openaire +2 more sources
Vision: Melanopsin as a Raumgeber [PDF]
Two new studies show that neural systems receiving inputs from the melanopsin-containing retinal ganglion cells encode spatial information and therefore see the world in more detail than previously thought.
Spitschan, M, Aguirre, G
openaire +3 more sources
Longitudinal Evaluation of Chromatic Pupillometry and Retinal Thickness in Dogs With Sudden Acquired Retinal Degeneration Syndrome. [PDF]
ABSTRACT Objective To determine longitudinal changes in chromatic pupillary light reflexes (cPLR) and retinal layers in dogs with sudden acquired retinal degeneration syndrome (SARDS). Animals Studied Clinical evaluation: Fifteen SARDS‐affected and nine control dogs.
Kim S +6 more
europepmc +2 more sources
An evaluation of melanopsin function and light exposure in depressive disorders [PDF]
Melanopsin cells in the eye signal environmental light to multiple brain areas including those for circadian rhythms, for controlling the pupil light reflex and mood.
Ojha, Govinda
core +1 more source
Melanopsin-mediated pupil function is impaired in Parkinson’s disease [PDF]
Parkinson’s disease (PD) is characterised by non-motor symptoms including sleep and circadian disruption. Melanopsin-expressing intrinsically photosensitive Retinal Ganglion Cells (ipRGC) transmit light signals to brain areas controlling circadian ...
Graham Kerr +10 more
core +1 more source
Spectral Tuning in Mammalian Melanopsins. [PDF]
Abstract Melanopsin is a light-sensitive G-protein coupled receptor responsible for essential visual and non-visual light-mediated behaviors in mammals. Human melanopsin shows maximal sensitivity (λmax) in the blue region of the spectrum (∼480 nm), and available evidence suggests that this spectral sensitivity may be retained across ...
McDowell RJ +3 more
europepmc +4 more sources
Light adaptation characteristics of melanopsin
Following photopigment bleaching, the rhodopsin and cone-opsins show a characteristic exponential regeneration in the dark with a photocycle dependent on the retinal pigment epithelium. Melanopsin pigment regeneration in animal models requires different pathways to rods and cones.
Pant, Mukund +3 more
openaire +3 more sources
Melanopsin: an exciting photopigment
The discovery that mice lacking rods and cones are capable of regulating their circadian rhythms by light provided the conceptual framework for the discovery of an entirely new photoreceptor system within the mammalian eye. We now know that a small subset of retinal ganglion cells are directly photosensitive and utilize an opsin/vitamin A-based ...
Hankins, M, Peirson, S, Foster, R
openaire +2 more sources
Melanopsin expression in the retinas of owls with different daily activity patterns
Melanopsin is a photopigment found in a subset of retinal ganglion cells that is responsible for generating a series of responses to light in organisms, such as circadian rhythm regulation, pupillary light reflex, and body temperature control.
Maria Júlia Vilani Naman +6 more
doaj +1 more source

