Results 41 to 50 of about 6,987 (212)

Characterization of the melanopsin gene (Opn4x) of diurnal and nocturnal snakes

open access: yesBMC Evolutionary Biology, 2019
Background A number of non-visual responses to light in vertebrates, such as circadian rhythm control and pupillary light reflex, are mediated by melanopsins, G-protein coupled membrane receptors, conjugated to a retinal chromophore.
Einat Hauzman   +3 more
doaj   +1 more source

Melanopsin-driven light adaptation in mouse vision. [PDF]

open access: yes, 2014
BACKGROUND: In bright light, mammals use a distinct photopigment (melanopsin) to measure irradiance for centrally mediated responses such as circadian entrainment.
Montemurro M. A.   +20 more
core   +1 more source

Melanopsin (Opn4) is an oncogene in cutaneous melanoma

open access: yesCommunications Biology, 2022
AbstractThe search for new therapeutical targets for cutaneous melanoma and other cancers is an ongoing task. We expanded this knowledge by evaluating whether opsins, light- and thermo-sensing proteins, could display tumor-modulatory effects on melanoma cancer.
Leonardo Vinícius Monteiro de Assis   +9 more
openaire   +3 more sources

M1 Intrinsically Photosensitive Retinal Ganglion Cells Integrate Rod and Melanopsin Inputs to Signal in Low Light

open access: yesCell Reports, 2019
Summary: Light influences various behaviors and physiological processes that occur outside of our conscious perception, including circadian photoentrainment, sleep, and even learning and mood.
Seul Ki Lee   +2 more
doaj   +1 more source

Adult Expression of Tbr2 Is Required for the Maintenance but Not Survival of Intrinsically Photosensitive Retinal Ganglion Cells

open access: yesFrontiers in Cellular Neuroscience, 2022
Retinal ganglion cells expressing the photopigment melanopsin are intrinsically photosensitive (ipRGCs). ipRGCs regulate subconscious non-image-forming behaviors such as circadian rhythms, pupil dilation, and light-mediated mood.
Sadaf Abed   +3 more
doaj   +1 more source

Melanopsin activates divergent phototransduction pathways in intrinsically photosensitive retinal ganglion cell subtypes

open access: yeseLife, 2023
Melanopsin signaling within intrinsically photosensitive retinal ganglion cell (ipRGC) subtypes impacts a broad range of behaviors from circadian photoentrainment to conscious visual perception.
Ely Contreras   +4 more
doaj   +1 more source

Mixed Palettes of Melanopsin Phototransduction [PDF]

open access: yesCell, 2018
Animal photoreceptors divide into two fundamental classes, ciliary and rhabdomeric. Jiang and colleagues demonstrate that this boundary is disregarded by the intrinsically photosensitive retinal ganglion cells of mammals. These neurons draw from phototransduction mechanisms of both classes, enriching the signals that they produce to drive a diversity ...
openaire   +2 more sources

Melanopsin Tristability for Sustained and Broadband Phototransduction [PDF]

open access: yesNeuron, 2015
Mammals rely upon three ocular photoreceptors to sense light: rods, cones, and intrinsically photosensitive retinal ganglion cells (ipRGCs). Rods and cones resolve details in the visual scene. Conversely, ipRGCs integrate over time and space, primarily to support "non-image" vision. The integrative mechanisms of ipRGCs are enigmatic, particularly since
Emanuel, Alan Joseph   +1 more
openaire   +2 more sources

Localization of melanopsin in the lamprey retina.

open access: yes, 2014
Localization of melanopsin visualized by in situ hybridization with an antisense probe for melanopsin (A) and immunohistochemistry with an anti-melanopsin antibody (B) in the lamprey retina. Melanopsin expression is observed in the inner horizontal cells
Takashi Nagata (336038)   +6 more
core   +1 more source

Melanopsin contributions to irradiance coding in the thalamo-cortical visual system.

open access: yesPLoS Biology, 2010
Photoreception in the mammalian retina is not restricted to rods and cones but extends to a subset of retinal ganglion cells expressing the photopigment melanopsin (mRGCs).
Timothy M Brown   +9 more
doaj   +1 more source

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