Results 41 to 50 of about 4,663 (179)

The Roles of Rods, Cones, and Melanopsin in Photoresponses of M4 Intrinsically Photosensitive Retinal Ganglion Cells (ipRGCs) and Optokinetic Visual Behavior

Frontiers in Cellular Neuroscience, 2018
Intrinsically photosensitive retinal ganglion cells (ipRGCs) mediate not only image-forming vision like other ganglion cells, but also non-image-forming physiological responses to light such as pupil constriction and circadian photoentrainment.
Melanie M. Schroeder, Krystal R. Harrison, Krystal R. Harrison, Elizabeth R. Jaeckel, Hunter N. Berger, Xiwu Zhao, Michael P. Flannery, Emma C. St. Pierre, Nancy Pateqi, Agnieszka Jachimska, Andrew P. Chervenak, Kwoon Y. Wong, Kwoon Y. Wong   +12 more
doaj   +1 more source

Melatonin Levels in 89 Individuals With Smith Magenis Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT In patients with Smith–Magenis syndrome (SMS), an inverted circadian rhythm of melatonin (MT) contributes to the sleep disturbance. Standard treatment of sleep disturbance with MT often leads to extremely high daytime MT levels, resulting in even more sleep disorders. We therefore retrospectively evaluated the MT data of 89 SMS patients.
Wiebe Braam, Ann C. M. Smith
wiley   +1 more source

Melanopsin Tristability for Sustained and Broadband Phototransduction [PDF]

Neuron, 2015
Mammals rely upon three ocular photoreceptors to sense light: rods, cones, and intrinsically photosensitive retinal ganglion cells (ipRGCs). Rods and cones resolve details in the visual scene. Conversely, ipRGCs integrate over time and space, primarily to support "non-image" vision. The integrative mechanisms of ipRGCs are enigmatic, particularly since
Emanuel, Alan Joseph, Do, Michael Tri Hoang   +1 more
openaire   +2 more sources

Extraocular Photoreception in Optic Lobes, Suckers, and Skin of Octopus vulgaris

Integrative Zoology, EarlyView.
Evidence of extra‐ocular photoreception in Octopus vulgaris (a) Diagram of the O. vulgaris different tissues considered: SPB, sucker proximal big; SPL, sucker proximal large; SM, sucker medium; SD, sucker distal; SK, skin; OL, optic lobes; RT, retina; (b‐d) Gene expression analysis of Ov‐GRK1 (red), Ov‐retinochrome (green), Ov‐rhodopsin (blue) mRNA ...
Valeria Maselli, Al‐Sayed Al‐Soudy, Mariangela Norcia, Stefania Galdiero, Sara Palladino, Emanuela Cirillo, Gianluca Polese, Anna Di Cosmo   +7 more
wiley   +1 more source

Melanopsin and Cone Photoreceptor Inputs to the Afferent Pupil Light Response

Frontiers in Neurology, 2019
Background: Retinal photoreceptors provide the main stage in the mammalian eye for regulating the retinal illumination through changes in pupil diameter, with a small population of melanopsin-expressing intrinsically photosensitive retinal ganglion cells
Andrew J. Zele, Andrew J. Zele, Prakash Adhikari, Prakash Adhikari, Dingcai Cao, Beatrix Feigl, Beatrix Feigl, Beatrix Feigl   +7 more
doaj   +1 more source

The Ecology of Human Sleep (EcoSleep) Cohort Study: Protocol for a longitudinal repeated measurement burst design study to assess the relationship between sleep determinants and outcomes under real‐world conditions across time of year

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary The interplay of daily life factors, including mood, physical activity, or light exposure, influences sleep architecture and quality. Laboratory‐based studies often isolate these determinants to establish causality, thereby sacrificing ecological validity.
Anna M. Biller, Nayab Fatima, Chrysanth Hamberger, Laura Hainke, Verena Plankl, Amna Nadeem, Achim Kramer, Martin Hecht, Manuel Spitschan   +8 more
wiley   +1 more source

Melanopsin: Another Way of Signaling Light [PDF]

Neuron, 2006
A subset of melanopsin-expressing retinal ganglion cells has been identified to be directly photosensitive (pRGCs), modulating a range of behavioral and physiological responses to light. Recent expression studies of melanopsin have provided compelling evidence that melanopsin is the photopigment of the pRGCs.
Peirson, Stuart, Foster, Russell G.
openaire   +2 more sources

Blue Light Exposure During Sleep in Type 1 Diabetes: Impacts on Glycemic Control and Psychosocial Health

Journal of Sleep Research, EarlyView.
ABSTRACT Light exposure at night is linked to increased risk for obesity and insulin resistance in the general population. While sleep health is recognized as a key component of diabetes management, there has been less emphasis on nighttime light exposure. This study aimed to investigate the effects of blue and white light exposure immediately prior to
Seok Jin Hong, Sarida Pratuangtham, Pamela Martyn‐Nemeth, Alana D. Steffen, Chang Gi Park, Sirimon Reutrakul   +5 more
wiley   +1 more source

Robust visual cortex evoked potentials (VEP) in Gnat1 and Gnat2 knockout mice

Frontiers in Cellular Neuroscience, 2022
Intrinsically photosensitive retinal ganglion cells (ipRGCs) express the photopigment melanopsin, imparting to themselves the ability to respond to light in the absence of input from rod or cone photoreceptors.
Michael D. Flood, Hannah L. B. Veloz, Samer Hattar, Joao L. Carvalho-de-Souza, Joao L. Carvalho-de-Souza, Joao L. Carvalho-de-Souza, Joao L. Carvalho-de-Souza   +6 more
doaj   +1 more source

Circadian regulation of reproduction and neoblast cell division in the catenulid flatworm Stenostomum virginianum (Platyhelminthes)

Photochemistry and Photobiology, EarlyView.
The circadian clock and melatonin coordinate homeostasis in many animals, yet their influence on reproduction and neoblast proliferation has only been shown in triclads. This study demonstrates that the early‐branching catenulid Stenostomum virginianum contains photoreceptive refractile bodies, synthesizes endogenous melatonin, and that exogenous ...
Daniel L. Stanton, Ian D. Deas, J. Kennon Smith, Samuel B. Robinson, Adam M. Reitzel, Julian P. S. Smith III   +5 more
wiley   +1 more source