Results 61 to 70 of about 6,987 (212)

Human visual cortex responds to isolated melanopsin-directed stimulation

, 2017
Melanopsin is expressed in a subset of retinal ganglion cells and mediates non-image-forming responses to light. It is unknown whether melanopsin contributes to conscious vision.
David H. Brainard, Aguirre, G., Manuel Spitschan, Frazzetta, G., Andrew S. Bock, Giulia Frazzetta, Spitschan, M. ; https://orcid.org/, Geoffrey K. Aguirre, Brainard, D., Bock, A.   +9 more
core   +1 more source

Functional characterisation of naturally occurring mutations in human melanopsin [PDF]

, 2018
Melanopsin is a blue light-sensitive opsin photopigment involved in a range of non-image forming behaviours, including circadian photoentrainment and the pupil light response.
Stuart N. Peirson, Steven Hughes, Mark W. Hankins, Jessica Rodgers   +3 more
core   +1 more source

The Ecology of Human Sleep (EcoSleep) Cohort Study: Protocol for a longitudinal repeated measurement burst design study to assess the relationship between sleep determinants and outcomes under real‐world conditions across time of year

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary The interplay of daily life factors, including mood, physical activity, or light exposure, influences sleep architecture and quality. Laboratory‐based studies often isolate these determinants to establish causality, thereby sacrificing ecological validity.
Anna M. Biller, Nayab Fatima, Chrysanth Hamberger, Laura Hainke, Verena Plankl, Amna Nadeem, Achim Kramer, Martin Hecht, Manuel Spitschan   +8 more
wiley   +1 more source

Novel pupillometry protocols for the early detection of melanopsin dysfunction in glaucoma [PDF]

, 2017
This thesis developed new pupillometry paradigms to objectively measure melanopsin function in humans with healthy or diseased eyes. It was determined that melanopsin function is independent of age and refractive error.
Adhikari, Prakash
core   +1 more source

Melanopsin Cell Dysfunction is Involved in Sleep Disruption in Parkinson’s Disease

Journal of Parkinson’s Disease, 2020
Background: Melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs) signal the environmental light to mediate circadian photoentrainment and sleep-wake cycles.
Beatrix Feigl, Sunila Dumpala, Graham K. Kerr, Andrew J. Zele   +3 more
doaj   +1 more source

A Broad Role for Melanopsin in Nonvisual Photoreception [PDF]

The Journal of Neuroscience, 2003
The rod and cone photoreceptors that mediate visual phototransduction in mammals are not required for light-induced circadian entrainment, negative masking of locomotor activity, suppression of pineal melatonin, or the pupillary light reflex. The photopigment melanopsin has recently been identified in intrinsically photosensitive retinal ganglion cells
Joshua J, Gooley, Jun, Lu, Dietmar, Fischer, Clifford B, Saper   +3 more
openaire   +2 more sources

A Double‐Blind Randomised Controlled Crossover Trial of the Effect of Blue‐Enriched Ambient Light on Sleep in Older Adults With Sleep Disturbance: The CleverLights Study

Journal of Sleep Research, EarlyView.
ABSTRACT Light interventions have been investigated for treating sleep disturbances in older adults; however, findings are mixed. This proof‐of‐concept trial investigated the effect of blue‐enriched ambient light on electroencephalographic (EEG) sleep in older adults with self‐reported poor sleep.
Teha B. Pun, Craig L. Phillips, Nathaniel S. Marshall, Matthew Rahimi, Rick Wassing, Maria Comas, Angela L. D'Rozario, Camilla M. Hoyos, Delwyn J. Bartlett, Wenye Hu, Sharon L. Naismith, Sean Cain, Svetlana Postnova, Ronald R. Grunstein, Christopher J. Gordon   +14 more
wiley   +1 more source

Photochemistry of retinal chromophore in mouse melanopsin [PDF]

Proceedings of the National Academy of Sciences, 2008
In mammals, melanopsin is exclusively expressed in intrinsically photosensitive retinal ganglion cells (ipRGCs), which play an important role in circadian photoentrainment and other nonimage-forming functions. These ipRGCs reside in the inner retina, far removed from the pigment epithelium, which synthesizes the 11-
Walker, Marquis T, Brown, R. Lane, Cronin, Thomas W, Robinson, Phyllis R   +3 more
openaire   +3 more sources

Circadian regulation of reproduction and neoblast cell division in the catenulid flatworm Stenostomum virginianum (Platyhelminthes)

Photochemistry and Photobiology, EarlyView.
The circadian clock and melatonin coordinate homeostasis in many animals, yet their influence on reproduction and neoblast proliferation has only been shown in triclads. This study demonstrates that the early‐branching catenulid Stenostomum virginianum contains photoreceptive refractile bodies, synthesizes endogenous melatonin, and that exogenous ...
Daniel L. Stanton, Ian D. Deas, J. Kennon Smith, Samuel B. Robinson, Adam M. Reitzel, Julian P. S. Smith III   +5 more
wiley   +1 more source

Melanopsin Driven Light Responses Across a Large Fraction of Retinal Ganglion Cells in a Dystrophic Retina

Frontiers in Neuroscience, 2020
Intrinsically photosensitive retinal ganglion cells (ipRGCs) express the photopigment melanopsin and project to central targets, allowing them to contribute to both image-forming and non-image forming vision.
Cyril G. Eleftheriou, Phillip Wright, Annette E. Allen, Daniel Elijah, Franck P. Martial, Robert J. Lucas   +5 more
doaj   +1 more source