Results 61 to 70 of about 4,663 (179)

Photochemistry of retinal chromophore in mouse melanopsin [PDF]

Proceedings of the National Academy of Sciences, 2008
In mammals, melanopsin is exclusively expressed in intrinsically photosensitive retinal ganglion cells (ipRGCs), which play an important role in circadian photoentrainment and other nonimage-forming functions. These ipRGCs reside in the inner retina, far removed from the pigment epithelium, which synthesizes the 11- cis
Walker, Marquis T, Brown, R. Lane, Cronin, Thomas W, Robinson, Phyllis R   +3 more
openaire   +3 more sources

Family History and Solar Insolation in Bipolar I Disorder

Acta Psychiatrica Scandinavica, Volume 153, Issue 4, Page 270-278, April 2026.
ABSTRACT Background Sunlight has profound impacts on physical and mental health, beyond vision, including effects on circadian rhythms, alertness, mood, and sleep. A family history of any mood disorders is strongly associated with psychiatric disorders including bipolar disorder.
M. Bauer, T. Glenn, E. D. Achtyes, M. Alda, E. Agaoglu, K. Altınbaş, O. A. Andreassen, E. Angelopoulos, R. Ardau, M. Aydin, Y. Ayhan, C. Baethge, R. Bauer, B. T. Baune, C. Balaban, C. Becerra‐Palars, A. P. Behere, H. Belete, T. Belete, G. Okawa Belizario, F. Bellivier, R. H. Belmaker, F. Benedetti, M. Berk, Y. Bersudsky, Ş. Bicakci, H. Birabwa‐Oketcho, T. D. Bjella, C. Brady, J. Cabrera, M. Cappucciati, A. M. Paredes Castro, W. Chen, E. Y. W. Cheung, S. Chiesa, M. Chanopoulou, M. Crowe, A. Cuomo, S. Dallaspezia, P. Desai, S. Dodd, B. Etain, A. Fagiolini, F. T. Fellendorf, E. Ferensztajn‐Rochowiak, J. G. Fiedorowicz, K. N. Fountoulakis, M. A. Frye, P. A. Geoffroy, M. J. Gitlin, A. Gonzalez‐Pinto, J. F. Gottlieb, P. Grof, B. C. M. Haarman, H. Harima, M. Hasse‐Sousa, C. Henry, L. Hoffding, J. Houenou, M. Imbesi, E. T. Isometsä, M. Ivkovic, S. Janno, S. Johnsen, F. Kapczinski, G. N. Karakatsoulis, M. Kardell, L. V. Kessing, S. J. Kim, B. König, T. L. Kot, M. Koval, M. Kunz, B. Lafer, M. Landén, E. R. Larsen, R. W. Licht, V. M. Ludwig, C. Lopez‐Jaramillo, A. MacKenzie, H. Østergaard Madsen, S. Alberte Kongstad A. Madsen, J. Mahadevan, A. Mahardika, K. Mahfoudh, M. Manchia, W. Marsh, M. Martinez‐Cengotitabengoa, J. Martini, K. Martiny, Y. Mashima, D. M. McLoughlin, A. N. R. Meesters, Y. Meesters, I. Melle, F. Meza‐Urzúa, E. Michaelis, P. Mikolas, Y. Ming Mok, S. Monteith, M. Moorthy, G. Morken, E. Mosca, A. A. Mozzhegorov, R. Munoz, S. V. Mythri, R. K. Nadella, T. Nakanotani, R. Ernst Nielsen, C. O'Donovan, A. Omrani, Y. Osher, U. Ouali, M. Pantovic‐Stefanovic, P. Pariwatcharakul, J. Petite, A. Pfennig, M. Pilhatsch, Y. Pica Ruiz, M. Pinna, M. Pompili, R. Porter, D. Quiroz, F. Diego Rabelo‐da‐Ponte, R. Ramesar, N. Rasgon, W. Ratta‐apha, M. Redahan, M. S. Reddy, A. Reif, E. Z. Reininghaus, J. Gringer Richards, P. Ritter, J. K. Rybakowski, L. Sathyaputri, A. M. Scippa, C. Simhandl, D. Smith, J. Smith, P. W. Stackhouse Jr, D. J. Stein, K. Stilwell, S. Strejilevich, K.‐P. Su, M. Subramaniam, A. Hatim Sulaiman, K. Suominen, A. J. Tanra, Y. Tatebayashi, W. Lin Teh, L. Tondo, C. Torrent, D. Tuinstra, T. Uchida, A. E. Vaaler, E. Vieta, B. Viswanath, C. Volf, K.‐J. Yang, M. Yoldi‐Negrete, O. Kaan Yalcinkaya, A. H. Young, Y. Zgueb, P. C. Whybrow   +163 more
wiley   +1 more source

The melanopsin system [PDF]

Neurology, 2011
The melanopsin system consists of retinal ganglion cells containing the photopigment melanospin, which are directly activated by light in the absence of inputs from the photoreceptors. These intrinsically photosensitive retinal ganglion cells (ipRGCs) detect environmental brightness; combine their direct, melanospin-triggered photoresponses with ...
openaire   +2 more sources

Mapping physiological inputs from multiple photoreceptor systems to dopaminergic amacrine cells in the mouse retina

Scientific Reports, 2017
In the vertebrate retina, dopamine is synthesized and released by a specialized type of amacrine cell, the dopaminergic amacrine cell (DAC). DAC activity is stimulated by rods, cones, and melanopsin-expressing intrinsically photosensitive retinal ...
Xiwu Zhao, Kwoon Y. Wong, Dao-Qi Zhang
doaj   +1 more source

Linking Photophobia, Sleep Disturbances, and Migraine Chronicity: Evidence From a Retrospective Analysis

Brain and Behavior, Volume 16, Issue 3, March 2026.
This study demonstrated that ictal photophobia was present in 89.8% and interictal photophobia in 93.4% of patients. Sleep disturbances were common, with 44.9% reporting difficulty falling asleep. Network analysis revealed stronger associations between interictal photophobia, daytime sleepiness, and medication overuse in chronic migraine compared to ...
Seden Demirci, Ezgi Uludüz, Sevim Eyüboğlu, Fatma Yardibi, Damla Hazal Sucu, Utku Topbaş, Aynur Özge, Derya Uludüz   +7 more
wiley   +1 more source

Distribution of melanopsin positive neurons in pigmented and albino mice: evidence for melanopsin interneurons in the mouse retina [PDF]

Frontiers in Neuroanatomy, 2014
Here we have studied the population of intrinsically photosensitive retinal ganglion cells (ipRGCs) in adult pigmented and albino mice. Our data show that although pigmented (C57Bl/6) and albino (Swiss) mice have a similar total number of ipRGCs, their distribution is slightly different: while in pigmented mice ipRGCs are more abundant in the temporal ...
Valiente-Soriano, FJ, García-Ayuso, D, Ortín-Martínez, A, Jiménez-López, M, Galindo-Romero, C, Villegas-Pérez, MP, Agudo-Barriuso, M, Vugler, AA, Vidal-Sanz, M   +8 more
openaire   +4 more sources

Pinopsin Regulates Melatonin Production and Daily Locomotor Activity: Functional Insights From Gene‐Edited Xenopus Tadpoles

Journal of Pineal Research, Volume 78, Issue 2, March 2026.
ABSTRACT Circadian rhythm alignment depends on environmental light detection via opsins. Pinopsin, originally identified in the pineal organ of birds and later in amphibian pineal complex and eyes, may play a role in this process, though its function has not been genetically tested.
Neda Heshami, Ricardo D. Romero, Flavio S. J. de Souza, Gabriel E. Bertolesi, Sarah McFarlane   +4 more
wiley   +1 more source

A Broad Role for Melanopsin in Nonvisual Photoreception [PDF]

The Journal of Neuroscience, 2003
The rod and cone photoreceptors that mediate visual phototransduction in mammals are not required for light-induced circadian entrainment, negative masking of locomotor activity, suppression of pineal melatonin, or the pupillary light reflex. The photopigment melanopsin has recently been identified in intrinsically photosensitive retinal ganglion cells
Joshua J, Gooley, Jun, Lu, Dietmar, Fischer, Clifford B, Saper   +3 more
openaire   +2 more sources

Daily rhythm of melanopsin-expressing cells in the mouse retina

Frontiers in Cellular Neuroscience, 2009
In addition to some other functions, melanopsin-expressing retinal ganglion cells (RGCs) constitute the principal mediators of the circadian photoentrainment, a process by which the suprachiasmatic nucleus (the central clock of mammals), adjusts daily to
Irene Gonzalez-Menend, Felipe Contreras, Rafael Cernuda-Cernuda, Jose M Garcia-Fernandez   +3 more
doaj   +1 more source

Materials and System Design for Self‐Decision Bioelectronic Systems

Advanced Materials, Volume 38, Issue 9, 12 February 2026.
This review highlights how self‐decision bioelectronic systems integrate sensing, computation, and therapy into autonomous, closed‐loop platforms that continuously monitor and treat diseases, marking a major step toward intelligent, self‐regulating healthcare technologies.
Qiankun Zeng, Hong Liu, Yongheng Zhang, Youbin Zheng, Xuyin Ding, Mengni Zhu, Guoyue Shi, Yan Wang, Hossam Haick, Min Zhang   +9 more
wiley   +1 more source