Results 71 to 80 of about 6,987 (212)
Robust visual cortex evoked potentials (VEP) in Gnat1 and Gnat2 knockout mice
Frontiers in Cellular Neuroscience, 2022 Intrinsically photosensitive retinal ganglion cells (ipRGCs) express the photopigment melanopsin, imparting to themselves the ability to respond to light in the absence of input from rod or cone photoreceptors.
Michael D. Flood +6 more
doaj +1 more source
Photochemistry and Photobiology, EarlyView.The left panel reports the measured time course data of melatonin concentration in the blood plasma of 17 BL‐Rs and 15 BL‐NRs at baseline, during a two‐hour stay in the dark, during a one‐hour light exposure to blue light, and again in the dark. The right panel shows the magnitude of melatonin concentration after 60 min of exposure to warm white, cool ...
Helmut Piazena +4 more
wiley +1 more source
A new method to quantify the human visual threshold from melanopsin sensitive ganglion cells
Frontiers in Cellular Neuroscience, 2023 Traditional photoreceptors utilize the chromophore retinal to absorb light coupled with a unique opsin protein to specify receptor spectral sensitivity.
Jeff Rabin +7 more
doaj +1 more source
Melanopsin: Another Way of Signaling Light [PDF]
Neuron, 2006 A subset of melanopsin-expressing retinal ganglion cells has been identified to be directly photosensitive (pRGCs), modulating a range of behavioral and physiological responses to light. Recent expression studies of melanopsin have provided compelling evidence that melanopsin is the photopigment of the pRGCs.
Peirson, Stuart, Foster, Russell G.
openaire +2 more sources
The Risk of Cardiovascular Diseases for Shift Workers in the Prospective Heinz Nixdorf Recall Study
American Journal of Industrial Medicine, Volume 69, Issue 10, Page 845-856, October 2026.ABSTRACT Background Shift work can disrupt circadian rhythms and is postulated to play a role in cardiovascular diseases (CVD). In the German prospective population‐based Heinz Nixdorf Recall Study, we analyzed longitudinal associations between shift work and night‐shift work with CVD.
Katharina Wichert +7 more
wiley +1 more source
Melatonin Levels in 89 Individuals With Smith Magenis Syndrome
American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2260-2272, October 2026.ABSTRACT In patients with Smith–Magenis syndrome (SMS), an inverted circadian rhythm of melatonin (MT) contributes to the sleep disturbance. Standard treatment of sleep disturbance with MT often leads to extremely high daytime MT levels, resulting in even more sleep disorders. We therefore retrospectively evaluated the MT data of 89 SMS patients.
Wiebe Braam, Ann C. M. Smith
wiley +1 more source
Melanopsin (Opn4) requirement for normal light-induced circadian phase shifting.
, 2002 The master circadian oscillator in the hypothalamic suprachiasmatic nucleus is entrained to the day/night cycle by retinal photoreceptors. Melanopsin (Opn4), an opsin-based photopigment, is a primary candidate for photoreceptor-mediated entrainment.
Castrucci, A.M. +7 more
core +1 more source
Acta Neuropathologica Communications, 2018 Parkinson’s disease (PD) patients often suffer from non-motor symptoms like sleep dysregulation, mood disturbances or circadian rhythms dysfunction. The melanopsin-containing retinal ganglion cells are involved in the control and regulation of these ...
Isabel Ortuño-Lizarán +6 more
doaj +1 more source
Journal of Sleep Research, Volume 35, Issue 5, October 2026.ABSTRACT Light exposure at night is linked to increased risk for obesity and insulin resistance in the general population. While sleep health is recognized as a key component of diabetes management, there has been less emphasis on nighttime light exposure. This study aimed to investigate the effects of blue and white light exposure immediately prior to
Seok Jin Hong +5 more
wiley +1 more source
Scientific Reports, 2017 In the vertebrate retina, dopamine is synthesized and released by a specialized type of amacrine cell, the dopaminergic amacrine cell (DAC). DAC activity is stimulated by rods, cones, and melanopsin-expressing intrinsically photosensitive retinal ...
Xiwu Zhao, Kwoon Y. Wong, Dao-Qi Zhang
doaj +1 more source