Results 91 to 100 of about 6,987 (212)

Melanopsin DNA aptamers can regulate input signals of mammalian circadian rhythms by altering the phase of the molecular clock

open access: yesFrontiers in Neuroscience
DNA aptamers can bind specifically to biomolecules to modify their function, potentially making them ideal oligonucleotide therapeutics. Herein, we screened for DNA aptamer of melanopsin (OPN4), a blue-light photopigment in the retina, which plays a key ...
Kazuo Nakazawa   +7 more
doaj   +1 more source

Firing and Receptive Field Properties of Melanopsin Retinal Ganglion Cells

open access: yes, 2010
Retinal ganglion cells that express the photopigment melanopsin (MGCs) are sparsely present in the retina. In rodents, they comprise 1-3% of the total number of retinal ganglion cells.
Aki Kawasaki
core  

The diverse roles of inhibition in identified neural circuits [PDF]

open access: yes, 2010
Inhibitory interneurons represent a diverse population of cell types in the central nervous system, whose general role is to suppress activity of target neurons.
Viney, Tim James
core   +1 more source

Rhodopsin and Melanopsin Contributions to the Early Redilation Phase of the Post-Illumination Pupil Response (PIPR).

open access: yesPLoS ONE, 2016
Melanopsin expressing intrinsically photosensitive Retinal Ganglion Cells (ipRGCs) entirely control the post-illumination pupil response (PIPR) from 6 s post-stimulus to the plateau during redilation after light offset.
Prakash Adhikari   +2 more
doaj   +1 more source

Blue light activates pulvinar nuclei in longstanding idiopathic photophobia: A case report

open access: yesNeuroImage: Clinical, 2019
Numerous pathologies can contribute to photophobia. When considering light transduction alone, photophobia may be triggered through melanopsin pathways (non-image forming), rod and cone pathways (image-forming), or some combination of the two.
Athanasios Panorgias   +4 more
doaj   +1 more source

Melanopsin in the human and chicken choroid

open access: yesExperimental Eye Research
The choroid embedded in between retina and sclera is essential for retinal photoreceptor nourishment, but is also a source of growth factors in the process of emmetropization that converts retinal visual signals into scleral growth signals. Still, the exact control mechanisms behind those functions are enigmatic while circadian rhythms are involved ...
Christian Platzl   +6 more
openaire   +2 more sources

Immunohistochemical evidence of a melanopsin cone in human retina.

open access: yes, 2006
PURPOSE: Melanopsin, expressed in a subset of intrinsically photosensitive ganglion cells that project to the suprachiasmatic nucleus (SCN), is involved in the photic entrainment of circadian rhythms and other non-image-forming functions (pupil light ...
Hut, Roelof, A.   +5 more
core   +1 more source

Melanopsin phototransduction is repurposed by ipRGC subtypes to shape the function of distinct visual circuits [PDF]

open access: yes, 2018
: Melanopsin is expressed in distinct types of intrinsically photosensitive retinal ganglion cells (ipRGCs), which drive behaviors from circadian photoentrainment to contrast detection. A major unanswered question is how the same photopigment, melanopsin,
Sonoda, Takuma   +3 more
core   +1 more source

Melanopsin-Driven Pupil Response and Light Exposure in Non-seasonal Major Depressive Disorder

open access: yesFrontiers in Neurology, 2018
Background: Melanopsin-expressing intrinsically photosensitive Retinal Ganglion Cells (ipRGCs) signal non-imaging forming effects of environmental light for circadian phoentrainment, the pupil light reflex, and mood regulation.
Beatrix Feigl   +7 more
doaj   +1 more source

Slow vision:Measuring melanopsin-mediated light effects in animal models

open access: yes, 2022
Mammalian retinas contain three specialized photoreceptors: the rods and cones in the outer retina, whose primary function is to support visual perception in dim and bright environments, respectively, and a small subset of retinal ganglion cells ...
Bano Otalora, Beatriz; id_orcid   +1 more
core   +3 more sources

Home - About - Disclaimer - Privacy