Results 81 to 90 of about 6,987 (212)
Journal of Comparative Neurology, Volume 534, Issue 9, September 2026.The annual turquoise killifish (Nothobranchius furzeri) cone photoreceptor mosaic is an ordered lattice but lacks regularity of cone subtypes in adulthood. The cone mosaic differs between life stages and has characteristics observed in other fishes adapted for life in turbid water.
Nicole C. L. Noel
wiley +1 more source
Neurology, 2011 The melanopsin system consists of retinal ganglion cells containing the photopigment melanospin, which are directly activated by light in the absence of inputs from the photoreceptors. These intrinsically photosensitive retinal ganglion cells (ipRGCs) detect environmental brightness; combine their direct, melanospin-triggered photoresponses with ...
openaire +2 more sources
The regulation of stem cell fate and its application in neural regeneration
Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He +3 more
wiley +1 more source
Daily rhythm of melanopsin-expressing cells in the mouse retina
Frontiers in Cellular Neuroscience, 2009 In addition to some other functions, melanopsin-expressing retinal ganglion cells (RGCs) constitute the principal mediators of the circadian photoentrainment, a process by which the suprachiasmatic nucleus (the central clock of mammals), adjusts daily to
Irene Gonzalez-Menend +3 more
doaj +1 more source
Circadian rhythms and chronotherapy in Alzheimer's disease: Mechanisms and therapeutic implications
Neuroprotection, Volume 4, Issue 3, Page 229-247, September 2026.Circadian dysregulation contributes to Alzheimer's disease through sleep disruption, clock‐gene dysfunction, neuroinflammation, impaired proteostasis, and metabolic imbalance. These alterations promote cognitive decline and disease progression, while circadian biomarkers and chronotherapeutic interventions offer opportunities for precision diagnosis ...
Bivek Singh +2 more
wiley +1 more source
Crosslinking and co-immunoprecipitation of β-arrestin 1 and β-arrestin 2 with melanopsin.
, 2014 β-arrestin 1 and β-arrestin 2 co-precipitate with melanopsin in a light- and phosphorylation-dependent manner. (A) Quantitation of β-arrestin 1 co-precipitation with wildtype (MEL) and phosphonull (PØ) melanopsin samples (top). Binding of β-arrestin 1 to
Phyllis R. Robinson (204369) +1 more
core +1 more source
Sensory Neuroscience, Volume 2, Issue 3, September 2026.Glaucoma is increasingly understood as a neurodegenerative disorder shaped by sleep and circadian physiology, not intraocular pressure alone. Sleep loss and obstructive sleep apnea suppress BDNF–TrkB neurotrophic signaling, impair sleep‐dependent glymphatic clearance, and trigger microglial neuroinflammation and vascular insult at the optic nerve head,
Karyme M. Alemán‐Villa +5 more
wiley +1 more source
Vision: Melanopsin and the Pharmacology of Photons
Current Biology, 2016 Using a targeted chemogenetic approach, a new study provides evidence for a unique pathway for neural processing of light information from melanopsin ganglion cells. These results suggest how light can have both alerting and sleep-promoting effects in mice.
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Altered Retinal Dopamine Homeostasis in Murine Models of Retinitis Pigmentosa
Journal of Neurochemistry, Volume 170, Issue 9, September 2026.Dopamine is an important catecholamine chemical messenger in the light‐sensing retina of the eye, where it serves multiple modulatory functions related to vision. This research studied the changes in the retinal dopamine system in two mouse models (P23H and rd10) of retinitis pigmentosa, which is a disease group of inherited retinal diseases that lead ...
Katri Vainionpää +11 more
wiley +1 more source
Journal of Pineal Research, Volume 78, Issue 5, September 2026.ABSTRACT Controlled studies have demonstrated that light supplementation benefits circadian entrainment, sleep and mood. Translating these findings into effective, real‐world usage of light supplementation is, however, challenging because naturalistic and supplemental light exposure are shaped by personal habits and environmental light conditions ...
Débora B. Constantino +18 more
wiley +1 more source