Results 101 to 110 of about 6,987 (212)

Evolution and functional characterisation of melanopsins in a deep-sea chimaera (elephant shark, Callorhinchus milii).

PLoS ONE, 2012
Non-visual photoreception in mammals is primarily mediated by two splice variants that derive from a single melanopsin (OPN4M) gene, whose expression is restricted to a subset of retinal ganglion cells.
Wayne I L Davies, Boon-Hui Tay, Lei Zheng, Janine A Danks, Sydney Brenner, Russell G Foster, Shaun P Collin, Mark W Hankins, Byrappa Venkatesh, David M Hunt   +9 more
doaj   +1 more source

NMDA Receptors Contribute to Retrograde Synaptic Transmission from Ganglion Cell Photoreceptors to Dopaminergic Amacrine Cells

Frontiers in Cellular Neuroscience, 2017
Recently, a line of evidence has demonstrated that the vertebrate retina possesses a novel retrograde signaling pathway. In this pathway, phototransduction is initiated by the photopigment melanopsin, which is expressed in a small population of retinal ...
Lei-Lei Liu, Nathan J. Spix, Dao-Qi Zhang   +2 more
doaj   +1 more source

In-silico predicted mouse melanopsins with blue spectral shifts deliver efficient subcellular signaling

Cell Communication and Signaling
Melanopsin is a photopigment belonging to the G Protein-Coupled Receptor (GPCR) family expressed in a subset of intrinsically photosensitive retinal ganglion cells (ipRGCs) and responsible for a variety of processes.
Dhanushan Wijayaratna, Filippo Sacchetta, Laura Pedraza-González, Francesca Fanelli, Tomohiro Sugihara, Mitsumasa Koyanagi, Senuri Piyawardana, Kiran Ghotra, Waruna Thotamune, Akihisa Terakita, Massimo Olivucci, Ajith Karunarathne   +11 more
doaj   +1 more source

Determining Light Intensity, Timing and Type of Visible and Circadian Light From an Ambulatory Circadian Monitoring Device

Frontiers in Physiology, 2019
During last decades, the way of life in modern societies has deeply modified the temporal adjustment of the circadian system, mainly due to the inappropriate use of artificial lighting and the high prevalence of social jet-lag.
Raquel Arguelles-Prieto, Maria-Angeles Bonmati-Carrion, Maria-Angeles Bonmati-Carrion, Maria Angeles Rol, Maria Angeles Rol, Juan Antonio Madrid, Juan Antonio Madrid   +6 more
doaj   +1 more source

Anatomy/Morphology of Melanopsin Retinal Ganglion Cells (MRGC) In the Human Retina: Their Number and Connections to the Central Nervous System

, 2010
The recent identification of a new type of photoreceptor as a subclass of retinal ganglion cells (RGCs) in rodents was seminal.1,2 These RGCs are intrinsically photosensitive through the expression of the photopigment melanopsin (mRGCs)
Alfredo A. Sadun; Valerio Carelli; Chiara La Morga; Jens Hannibal; Fred Ross-Cisneros
core  

Measuring and using light in the melanopsin age

Trends in Neurosciences, 2014
Light is a potent stimulus for regulating circadian, hormonal, and behavioral systems. In addition, light therapy is effective for certain affective disorders, sleep problems, and circadian rhythm disruption. These biological and behavioral effects of light are influenced by a distinct photoreceptor in the eye, melanopsin-containing intrinsically ...
Lucas, Robert J, Peirson, Stuart N, Berson, David M, Brown, Timothy M, Cooper, Howard M, Czeisler, Charles A, Figueiro, Mariana G, Gamlin, Paul D, Lockley, Steven W, O'Hagan, John B, Price, Luke L A, Provencio, Ignacio, Skene, Debra J, Brainard, George C   +13 more
openaire   +4 more sources

Illumination by short-wavelength light inside the blind spot decreases light detectability

iScience
Summary: Although the optic disk corresponding to the blind spot contains no classical photoreceptors, it contains photopigment melanopsin. To clarify whether melanopsin is involved in light detection, we conducted detection tasks for light stimuli ...
Marina Saito, Kentaro Miyamoto, Ikuya Murakami   +2 more
doaj   +1 more source

Temporal, spatial and adaptation characteristics of melanopsin inputs to the human pupil light reflex [PDF]

, 2016
This thesis advanced understanding of the timing, spatial and adaptation properties of the human pupil light reflex (PLR). It developed new functional measures of the eye's melanopsin cells, which regulate circadian rhythms and pupil size, and are ...
Joyce, Daniel S.
core  

Melanopsin for precise optogenetic activation of astrocyte-neuron networks

, 2020
Optogenetics has been widely expanded to enhance or suppress neuronal activity and it has been recently applied to glial cells. Here, we have used a new approach based on selective expression of melanopsin, a G-protein-coupled photopigment, in astrocytes
Ramírez-Franco, Jorge, Perea, Gertrudis, Hernández-Vivanco, Alicia, Martín-Fernández, Mario, Mederos, Sara, Yang, A., Navarrete, Marta, Boyden, E.S.   +7 more
core   +1 more source

The Role of TASK-3 Two-Pore Domain Potassium Channels in the Entrainment of Mammalian Circadian Rhythms [PDF]

, 2014
In mammals light is the principal timing cue for alignment of physiology to the external environment. Illumination from the unrelenting 24-hour day-night cycle enters the biological system and is communicated to the master pacemaker, the suprachiasmatic
Atkinson, Lynsey A
core