Results 111 to 120 of about 6,987 (212)

The Post-illumination Pupil Response (PIPR) Is Associated With Cognitive Function in an Epidemiologic Cohort Study

Frontiers in Neurology, 2019
We conducted a cross-sectional study on 403 participants in the 10-year follow-up examination of the Beaver Dam Offspring Study. The participants included 172 male and 231 female, with age ranging from 33 to 81 years (mean ± SD, 60.7 ± 9.3).
Yanjun Chen, Alex A. Pinto, Adam J. Paulsen, Carla R. Schubert, Laura M. Hancock, Barbara E. Klein, Ron Klein, Karen J. Cruickshanks, Karen J. Cruickshanks   +8 more
doaj   +1 more source

Pupil responses to melanopsin-isolating stimuli as a potential diagnostic biomarker for glaucoma.

PLoS ONE
PurposeTo test whether differences in pupil responses to melanopsin-isolating spectral stimuli in glaucoma may be useful as a diagnostic biomarker.MethodsSpectral stimuli were presented to 20 glaucoma and 15 age-similar healthy control participants ...
Jonathan Denniss, Riccardo Cheloni, Joel T Martin, Manuel Spitschan   +3 more
doaj   +1 more source

Melanopsin-driven responses in the human brain

, 2014
Photopic vision arises from three classes of cones (L, M and S) as well as from the recently discovered intrinsically photosensitive retinal ganglion cells (ipRGCs), which contain melanopsin.
Aguirre, G., Luu, L., Spitschan, M. ; https://orcid.org/, Datta, R., Brainard, D.   +4 more
core   +1 more source

Immunohistochemical localization of melanopsin to ganglion cells identified by retrograde tracing in the lamprey retina.

, 2014
Melanopsin-expressing cells were immunohistochemically stained with the anti-melanopsin antibody (A, green) and ganglion cells were labeled by retrograde tracing with neurobiotin (B, magenta).
Takashi Nagata (336038), Emi Kawano-Yamashita (158057), Hisao Tsukamoto (633790), Mitsumasa Koyanagi (158063), Lanfang Sun (633789), Akihisa Terakita (8031), Yuji Furutani (633791)   +6 more
core   +1 more source

Melanopsin in ocular tissue after corneal abrasion

Melanopsin is a non-image forming photoreactive protein that has diverse roles in multiple tissues. This study examines how melanopsin expression changes after corneal abrasion.
Jenike, Ana
core   +1 more source

Anatomy/Morphology of Melanopsin Retinal Ganglion Cells (MRGC) In the Human Retina: Their Number and Connections to the Central Nervous System (PowerPoint)

, 2010
The recent identification of a new type of photoreceptor as a subclass of retinal ganglion cells (RGCs) in rodents was seminal.1,2 These RGCs are intrinsically photosensitive through the expression of the photopigment melanopsin (mRGCs)
Alfredo A. Sadun; Valerio Carelli; Chiara La Morga; Jens Hannibal; Fred Ross-Cisneros
core  

Melanopsin: photoreceptors, physiology and potential

, 2019
The discovery of melanopsin-expressing photosensitive retinal ganglion cells (pRGCs) has led to a fundamental change in our understanding of retinal light detection.

core   +1 more source

Exploring the relationship between melanopsin gene variants, sleep, and markers of brain health

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION Melanopsin is a photopigment with roles in mediating sleep and circadian‐related processes, which are often disrupted in Alzheimer's disease (AD). Melanopsin also impacts cognition and synaptogenesis. This study investigated the associations
Ayeisha Milligan Armstrong, Eleanor O'Brien, Tenielle Porter, Vincent Dore, Pierrick Bourgeat, Paul Maruff, Christopher C. Rowe, Victor. L. Villemagne, Stephanie R. Rainey‐Smith, Simon M. Laws, the AIBL Research Group   +10 more
doaj   +1 more source

Excitación melanopsinica en condiciones de iluminación natural y artificial

Anales (Asociación Física Argentina), 2018
Biological adaptation to sunlight evolved over millions of years. The intrusion of artificial lighting has disrupted this relationship with the natural environment.
O. U. Preciado, L. A. Issolio, E. Manzano, E. Colombo, P. A. Barrionuevo   +4 more
doaj  

Addition of human melanopsin renders mammalian cells photoresponsive.

, 2005
A small number of mammalian retinal ganglion cells act as photoreceptors for regulating certain non-image forming photoresponses. These intrinsically photosensitive retinal ganglion cells express the putative photopigment melanopsin.
Tarttelin, E. E., Bellingham, J., R. J. Lucas, E. E. Tarttelin, Melyan, Z., Z. Melyan, J. Bellingham, Hankins, M. W., M. W. Hankins, Lucas, R. J.; id_orcid   +9 more
core   +1 more source