Results 131 to 140 of about 397,235 (339)
Presence of transcription regulatory elements within an intron of the virus-inducible murine TIMP gene. [PDF]
, 1988 Benoit Coulombe +4 more
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Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer
Advanced Science, EarlyView.Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska +18 more
wiley +1 more source
Hepatology, EarlyView., 2022 Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo +14 more
wiley +1 more source
Variation of tRNA modifications with and without intron dependency
Frontiers in GeneticstRNAs have recently gained attention for their novel regulatory roles in translation and for their diverse functions beyond translation. One of the most remarkable aspects of tRNA biogenesis is the incorporation of various chemical modifications, ranging
Sachiko Hayashi
doaj +1 more source
Coevolution Theory of the Genetic Code at Age Forty: Pathway to Translation and Synthetic Life
Life, 2016 The origins of the components of genetic coding are examined in the present study. Genetic information arose from replicator induction by metabolite in accordance with the metabolic expansion law.
J. Tze-Fei Wong +4 more
doaj +1 more source
, 2006 If genome space is finite with little, if any, DNA that is not functional under some circumstance, then potential conflicts between different forms of genomic information must be resolved by appropriate trade-offs. These trade-offs sometimes require that genes accommodate spacers, introns, and simple sequence elements.
openaire +2 more sources
Structural Variations Associated with Adaptation and Coat Color in Qinghai‐Tibetan Plateau Cattle
Advanced Science, EarlyView.This study reveals the landscape of structural variants in Qinghai‐Tibetan Plateau cattle through long‐read sequencing. Discoveries include metabolic and oxygen‐regulation gene variants, along with a 2‐Mb KIT‐containing inversion and translocations responsible for cattle gray coat. These findings highlight the significant role of structural variants in
Xiaoting Xia +39 more
wiley +1 more source
CD8+ T cell memory is sustained in mice by hepatic stellate cells
Hepatology, EarlyView., 2022 HSC role in memory CD8+ T cell maintenance. Abstract Background and Aims Long‐lasting immunological memory is the ultimate goal of vaccination. Homeostatic maintenance of memory CD8+ cytotoxic T cells (MemCD8TCs) is thought to be mediated by IL‐15/IL‐15R heterodimer (15HD)‐expressing myeloid cells.
Yi‐Ting Chen +4 more
wiley +1 more source
Proceedings of the Japan Academy. Series B, Physical and Biological SciencesFrom the biota beneath the sea ice in Lake Saroma, which is adjacent to Sea of Okhotsk, a diatom culture of Saroma 16 was isolated. Strutted processes and a labiate process in Saroma 16 were characteristic of those in Thalassiosira nordenskioeldii ...
Yoshie UCHIDA +8 more
doaj +1 more source
The wheat cytochrome oxidase subunit II gene has an intron insert and three radical amino acid changes relative to maize [PDF]
, 1984 Linda Bonen +2 more
openalex +1 more source