Results 131 to 140 of about 245,400 (261)

A Cytosine‑Bulged (3+1) Hybrid G‑Quadruplex Formed by the Chicken DNA Replication Origin

Chemistry – A European Journal, EarlyView.
The first high‐resolution structure of an OGRE‐derived G‐quadruplex from the chicken β‐globin replication origin reveals an intramolecular three‐layer (3+1) hybrid fold with a cytosine bulge and an unprecedented 5'‐outer‐quartet anti guanine, creating a distinctive surface for molecular recognition.
Yingying You, Monica Ching Suen, Haitao Miao, Yanyan Geng, Rahman Ud Din, Mu Yuan, Qiang Xue, Xiaoting Li, Naining Xu, Zhihong Guo, Hon‐Ming Lam, Kwok‐Wai Lo, Changdong Liu, Guang Zhu   +13 more
wiley   +1 more source

Mobile intron RNA from a bacterial predator accumulates in dead archaeal cells. [PDF]

Sci Rep
Kizina J, Lonsing A, Harder J.
europepmc   +1 more source

Arabidopsis AUGMIN8 Contains Two Independent Microtubule Association Domains

Cytoskeleton, EarlyView.
ABSTRACT Plant cells create a plasma membrane‐associated network of microtubules that are nucleated by γ‐tubulin ring complexes primarily through microtubule‐dependent microtubule nucleation (MDMN). This dynamic array organizes into specific patterns in response to developmental and environmental cues to influence primary cell wall construction.
Naveen K. Chana, Timothy Cioffi, Sidney L. Shaw   +2 more
wiley   +1 more source

In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans

Cytoskeleton, EarlyView.
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley   +1 more source

Recurrent Modular Assembly Drives Independent Origins of Group II Introns Encoding LAGLIDADG Homing Endonucleases. [PDF]

Genome Biol Evol
Liu F, Jin S, Du Q.
europepmc   +1 more source

Long-range Intron-Exon and Intron-Intron Pairings Involved in Self-splicing of Class II Catalytic Introns

Cold Spring Harbor Symposia on Quantitative Biology, 1987
F, Michel, A, Jacquier
openaire   +2 more sources

Identification of a Functional CYP2C8 Variant Allele that Alters Splicing, Reduces Protein Expression, and Increases Drug Exposure

Clinical Pharmacology &Therapeutics, EarlyView.
This study investigated genetic determinants of the pharmacokinetics of the CYP2C8 index drugs repaglinide and gemfibrozil, and their interaction in healthy participants. Sequencing data from a study with montelukast revealed a novel functional CYP2C8 allele (rs2071426, CYP2C8*19), predicted to create an intronic splice donor site.
Anssi J. H. Mykkänen, Päivi Hirvensalo, Kathrin Klein, Dorota Kaminska, Markus Grube, Tuija Tapaninen, Johanna I. Kiiski, Mikko Neuvonen, Ville T. Männistö, Jussi Pihlajamäki, Mladen Tzvetkov, Matthias Schwab, Aleksi Tornio, Janne T. Backman, Mikko Niemi   +14 more
wiley   +1 more source

Insights into intraspecific variation and genotyping of <i>Ganoderma lingzhi</i> through pan-mitogenome analysis. [PDF]

IMA Fungus
Li J, Zhang C, Ni Y, Sun L, Cheng X, Liu C.   +5 more
europepmc   +1 more source

The role of Rho GTPases in facial morphogenesis

Developmental Dynamics, EarlyView.
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley   +1 more source

DNA Methylation Variation in Blood Cells may Impact Platelet Function. [PDF]

TH Open
Teichman J, Chen MH, Thibord F, Chan MV, Nkambule BB, Lachapelle AR, Ma J, Joehanes R, Liu C, Aponte AM, Panicker SR, Kanthi Y, Levy D, Johnson AD.   +13 more
europepmc   +1 more source