Results 191 to 200 of about 232,441 (272)

Construction of a yeast strain devoid of mitochondrial introns and its use to screen nuclear genes involved in mitochondrial splicing. [PDF]

, 1987
Bertrand Séraphin, Aren Boulet, M. Simon, G. Faye   +3 more
openalex   +1 more source

Purine Chemistry in the Early RNA World at the Origins of Life: From RNA and Nucleobases Lesions to Current Key Metabolic Routes

ChemBioChem, EarlyView.
In the nascent processes of the beginnings and evolution of life, nucleobases and especially purines, ribonucleos(t)ides and primitive RNAs have been continuously modified. A RNA‐peptide world and key metabolic pathways probably have emerged from the corresponding chemical modifications resulting from adenine deamination, purine alkylation and ...
Jean‐Luc Décout, Marie‐Christine Maurel   +1 more
wiley   +1 more source

Expansion of the tmRNA sequence database and new tools for search and visualization. [PDF]

NAR Genom Bioinform
Nawrocki EP, Petrov AI, Williams KP.
europepmc   +1 more source

Lienhwalides: Unique Tropolone–Maleidride Hybrids from Hypoxylon lienhwacheense

ChemBioChem, EarlyView.
Lienhwalides are novel tropolone–maleidride hybrid molecules unique in nature. Absolute configuration is solved by semisynthetic approaches and X‐ray analysis. Interplay between both lwt and lwm biosynthetic gene clusters is responsible for the production of lienhwalides.
Katharina Schmidt, Esteban Charria‐Girón, Tatiana E. Gorelik, Christian Kleeberg, Jackson M. Muema, Simone Heitkämper, Bart Verwaaijen, Eric Kuhnert, Jennifer Gerke, Jörn Kalinowski, Kevin D. Hyde, Marc Stadler, Russell Cox, Frank Surup   +13 more
wiley   +1 more source

Different clinical and genetic features of Alagille patients with progressive disease versus a jaundice‐free course

JGH Open, Volume 6, Issue 12, Page 839-845, December 2022., 2022
This study highlighted the different disease courses of Alagille syndrome patients with progressive disease (PD) or the jaundice‐free (JF) courses based on clinical follow‐up. Patients in the JF group had a favorable outcome and longer native liver survival than the PD group.
Che‐Ming Chiang, Yung‐Ming Jeng, Ming‐Chih Ho, Ming‐Wei Lai, Huei‐Ying Li, Pei‐Lung Chen, Ni‐Chung Lee, Jia‐Feng Wu, Yu‐Chun Chiu, Bang‐Yu Liou, Yen‐Hsuan Ni, Hong‐Yuan Hsu, Mei‐Hwei Chang, Huey‐Ling Chen   +13 more
wiley   +1 more source

<i>Nigromargaritatarda</i> gen. et sp. nov. and distribution of an intron position class within <i>Pleosporales</i>. [PDF]

IMA Fungus
Li MY, Sun X, Liu YQ, Qin SH, Li M, He XL.   +5 more
europepmc   +1 more source

Identification of splicing signals in introns of yeast mitochnodrial split genes: mutational alterations in intron bI 1 and secondary structures in related introns [PDF]

, 1982
Carlo Schmelzer, Cornelia Schmidt, Rudolf J. Schweyen   +2 more
openalex   +1 more source

The Heterotaxy Gene CCDC11 Is Important for Cytokinesis via RhoA Regulation

Cytoskeleton, EarlyView.
ABSTRACT Mutations in CCDC11 (cfap53) have been identified in multiple patients with heterotaxy (Htx), a disorder of left–right (LR) patterning of the internal organs. In Xenopus, depletion of Ccdc11 causes defects in LR patterning, recapitulating the patient phenotype. Upon Ccdc11 depletion, monociliated cells of the Left–Right Organizer (LRO) exhibit
Saurabh S. Kulkarni, Rachel E. Stephenson, Sarah Amalraj, Angelo Arrigo, Ewelina Betleja, James J. Moresco, John R. Yates III, Moe R. Mahjoub, Ann L. Miller, Mustafa K. Khokha   +9 more
wiley   +1 more source

Prp16 enables efficient splicing of introns with diverse exonic consensus elements in the short-intron rich <i>Cryptococcus neoformans</i> transcriptome. [PDF]

RNA Biol
Negi MS, Krishnan VP, Saraf N, Vijayraghavan U.   +3 more
europepmc   +1 more source

Sequence-dependent and -independent effects of intron-mediated enhancement learned from thousands of random introns. [PDF]

Nucleic Acids Res
Kowal EJK, Sakai Y, McGurk MP, Pasetsky ZJ, Burge CB.   +4 more
europepmc   +1 more source