Results 211 to 220 of about 416,899 (328)

Splice site diversity and abundance of noncanonical introns in diplonemids (Diplonemea, Euglenozoa). [PDF]

RNA
Thakur PK, Butenko A, Karásek F, Svobodová M, Faktorová D, Pavlisková H, Varga V, Horák A, Lukeš J, Staněk D.   +9 more
europepmc   +1 more source

Navigating the Genetic Risk of Chemotherapy‐Induced Hearing Loss in the Stria Vascularis

Clinical Pharmacology &Therapeutics, EarlyView.
Cisplatin is a chemotherapy drug that causes permanent hearing loss by damaging a critical tissue lining the inner ear, called the stria vascularis (SV). Currently, the molecular mechanisms of SV damage are largely unknown and the incidence of ototoxicity in patients cannot be reliably predicted.
Tara Lazetic, Deanne Nixie R. Miao, Britt I. Drögemöller, Alain Dabdoub, Julia M. Abitbol   +4 more
wiley   +1 more source

Promoter Specificity and Transcription Levels Modulate <i>Trans</i>-Splicing Efficiency at the <i>mod</i>(<i>mdg4</i>) Locus in <i>Drosophila</i>. [PDF]

Int J Mol Sci
Beginyazova O, Soldatova IV, Georgiev P, Tikhonov M.   +3 more
europepmc   +1 more source

Improvement of EPO Transgene Detection From Polymeric Dried Blood Spots for Antidoping Application

Drug Testing and Analysis, EarlyView.
This article presents an optimized protocol for gene doping detection. Starting from one spot DBS (20 μL), concentrated DNA was obtained and real‐time PCR parameters were adjusted for increased detection. Robust detection of 5000 copies/mL of transgene was validated for polymeric device TASSO M‐20.
Alexandre Marchand, Ingrid Roulland, Magnus Ericsson   +2 more
wiley   +1 more source

Identification of molecular markers associated with comb traits through genome-wide association study on a specialized strain of yellow feathered broilers. [PDF]

Poult Sci
Tu Y, Xu S, Liu Y, Zhang M, Ma J, Ju X, Shan Y, Ji G, Shu J.   +8 more
europepmc   +1 more source

Myomaker and Myomixer are required for craniofacial myoblast fusion in zebrafish

Developmental Dynamics, EarlyView.
Abstract Background Craniofacial and trunk skeletal muscles are derived from different progenitor populations during development. Trunk skeletal muscles contain mostly multinucleated myofibers that are formed through myoblast fusion. However, myoblast fusion in craniofacial muscles and its molecular regulation are not well understood.
Zhanxiong Zhang, Pengzheng Yong, Qiaomu Hu, Shaojun Du   +3 more
wiley   +1 more source

Oncogenic DEAD-box ATPase DDX41 establishes transcript ensembles via CLK3-dependent and -independent mechanisms. [PDF]

Nat Commun
Kim JA, Shen S, Jurotich CM, D'Souza SS, Caldon JJ, Slukvin II, Churpek JE, Keles S, Bresnick EH.   +8 more
europepmc   +1 more source

Identification of novel genes regulating the development of the palate

Developmental Dynamics, EarlyView.
Abstract Background The International Mouse Phenotyping Consortium (IMPC) has generated thousands of knockout mouse lines, many of which exhibit embryonic or perinatal lethality. Using micro‐computed tomography (micro‐CT), the IMPC has created and publicly released three‐dimensional image data sets of embryos from these lethal and subviable lines.
Ashwin Bhaskar, Sophie Astrof
wiley   +1 more source

Efficient genome editing by CRISPR-Cas12a in common wheat via shoot apical meristem delivery. [PDF]

Plant Physiol
Luo W, Ors S, Fang H, Zeng M, Cheng Y, Sidawy AE, Qi Y.   +6 more
europepmc   +1 more source

Methylation of single sites within the herpes simplex virus tk coding region and the simian virus 40 T-antigen intron causes gene inactivation.

, 1994
A. Graessmann, Gunnar Sandberg, Eva Guhl, M. Graessmann   +3 more
openalex   +2 more sources