Results 231 to 240 of about 232,441 (272)
Human DDIT4L intron retention contributes to cognitive impairment and amyloid plaque formation. [PDF]
Li KC+14 more
europepmc +1 more source
The RNA Binding Protein Bcas2 is Required for Antibody Class Switch in Activated‐B Cells
Bcas2 recruits DHX15 and SRSF7 to form a protein complex for the splicing of CSR‐related mRNA at the 5' ss and 3' ss, generating two mature mRNA isoforms, which are ultimately translated into CSR‐related proteins. These CSR‐related proteins bind to DNA associated with antibodies, affecting the DSB repair of the relevant DNA after AID induction, thereby
Yu Chen+29 more
wiley +1 more source
Pervasive Conservation of Intron Number and Other Genetic Elements Revealed by a Chromosome-level Genome Assembly of the Hyper-polymorphic Nematode Caenorhabditis brenneri. [PDF]
Teterina AA+3 more
europepmc +1 more source
The green side of splicing: algal spliceosome shows remarkable structural conservation. [PDF]
Galej WP.
europepmc +1 more source
ABSTRACT Background Adenoid cystic carcinoma (ACC) is an aggressive therapy‐resistant head and neck cancer with a high frequency of local recurrences and distant metastases. Activation of the MYB gene, encoding an oncogenic master transcription factor, is the key genomic hallmark of ACC and a potential therapeutic target. Here, we have investigated the
Fredrik Jäwert+5 more
wiley +1 more source
Enrichment of rare CFTR variants in Finnish patients with congenital chloride diarrhea. [PDF]
Wedenoja S+4 more
europepmc +1 more source
Extremely short 20–33 nucleotide introns are the standard length inParamecium tetraurelia
Chris B. Russell+2 more
openalex +2 more sources
Metabolic activities are selective modulators for individual segmentation clock processes. [PDF]
Matsuda M, Lázaro J, Ebisuya M.
europepmc +1 more source