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Biochemical and Biophysical Research Communications, 2005
MicroRNAs (miRNAs), small single-stranded regulatory RNAs capable of interfering with intracellular mRNAs that contain partial complementarity, are useful for the design of new therapies against cancer polymorphism and viral mutation. MiRNA was originally discovered in the intergenic regions of the Caenorhabditis elegans genome as native RNA fragments ...
Shao-Yao, Ying, Shi-Lung, Lin
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MicroRNAs (miRNAs), small single-stranded regulatory RNAs capable of interfering with intracellular mRNAs that contain partial complementarity, are useful for the design of new therapies against cancer polymorphism and viral mutation. MiRNA was originally discovered in the intergenic regions of the Caenorhabditis elegans genome as native RNA fragments ...
Shao-Yao, Ying, Shi-Lung, Lin
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Frühe Introns – späte Introns?
Biologie in unserer Zeit, 1995AbstractIntrons nennt man Nucleinsäuresequenzen, die mitten in Genregionen eingefügt sind, letztlich aber nicht in Polypeptidsequenzen übersetzt werden. Auch Prokaryoten und sogar Viren können unterbrochene Gene besitzen, aber nur bei den Eukaryoten findet man die „klassischen”︁ Introns, die dort fast alle Strukturgene zerstückeln.
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Blood, 2013
In this issue of Blood, Yuan et al provide evidence that processing of the first intronic sequence within the von Willebrand factor (vWF) gene facilitates expression by endothelial cells regardless of the source of the intron, while intron processing is irrelevant for vWF expression by megakaryocytes.(1)
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In this issue of Blood, Yuan et al provide evidence that processing of the first intronic sequence within the von Willebrand factor (vWF) gene facilitates expression by endothelial cells regardless of the source of the intron, while intron processing is irrelevant for vWF expression by megakaryocytes.(1)
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Science, 2003
Recently, attention has been drawn to eukaryotic genomes with very few introns ( [1][1], [2][2] ) and to the biased position of introns within genes ( [3][3] ). We show here that intron-poor eukaryotes for which genome data is available have a 5′ bias in the position of their introns within ...
Mourier, Tobias, Jeffares, Daniel C
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Recently, attention has been drawn to eukaryotic genomes with very few introns ( [1][1], [2][2] ) and to the biased position of introns within genes ( [3][3] ). We show here that intron-poor eukaryotes for which genome data is available have a 5′ bias in the position of their introns within ...
Mourier, Tobias, Jeffares, Daniel C
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Trends in Genetics, 2006
Eukaryotic genes are interrupted by spliceosomal introns, which are removed from gene transcripts. The number of introns per gene varies by more than two orders of magnitude between species, implying that there has been extensive intron loss and/or gain throughout eukaryotic evolution.
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Eukaryotic genes are interrupted by spliceosomal introns, which are removed from gene transcripts. The number of introns per gene varies by more than two orders of magnitude between species, implying that there has been extensive intron loss and/or gain throughout eukaryotic evolution.
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Mobile Introns and Intron-Encoded Proteins
Science, 1989P S, Perlman, R A, Butow
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