Results 271 to 280 of about 482,093 (336)

Genome-wide association and functional annotation analyses reveal candidate genes and pathways associated with various ewe longevity indicators in U.S. Katahdin sheep. [PDF]

Front Genet
Pinto LFB, Lewis RM, Rocha AO, Freking BA, Murphy TW, Wilson CS, Nilson SM, Burke JM, Brito LF.   +8 more
europepmc   +1 more source

Genomic Heterogeneity in a Natural Archaeal Population Suggests a Model of tRNA Gene Disruption [PDF]

, 2012
FUJISHIMA, Kosuke, KANAI, Akio, NUNOURA, Takuro, SUGAHARA, Junichi, TAKAI, Ken, TAKAKI, Yoshihiro, TAKAMI, Hideto, TOMITA, Masaru, 富田, 勝, 布浦, 拓郎, 菅原, 潤一, 藤島, 皓介, 金井, 昭夫, 高井, 研, 高木, 善弘, 高見, 英人   +15 more
core   +1 more source

Alu Overexpression Leads to an Increased Double‐stranded RNA Signature in Dermatomyositis

Arthritis &Rheumatology, Accepted Article.
Objective Dermatomyositis is an autoimmune condition characterized by a high interferon signature of unknown etiology. Because coding sequences constitute <1.2% of our genomes, there is a need to explore the role of the non‐coding genome in disease pathogenesis.
Rayan Najjar, Andrew Mammen, Tomas Mustelin   +2 more
wiley   +1 more source

Phylogenetic and evolutionary insights from 30 newly-assembled <i>Onygenales</i> Mitochondrial Genomes: co-evolution of introns and HEGs shapes mitogenome size variation. [PDF]

IMA Fungus
Romão HAA, Moreira TR, Corvalán LCJ, de Melo-Ximenes AA, Bailão AM, Borges CL, Dias RO, Nunes R.   +7 more
europepmc   +1 more source

Transcriptomic functional characterization of recombinant adeno‐associated virus producing cell line adapted to suspension‐growth

Biotechnology Progress, EarlyView.
Abstract Recombinant adeno‐associated virus (rAAV) is a widely used delivery vehicle in gene therapy. A scalable production technology is essential for its wide clinical applications. We have taken a synthetic biology approach to generate HEK293‐based cell lines which harbor integrated genetic elements encoding essential AAV and adenoviral helper ...
Han‐Jung Kuo, Prahalad Srinivasan, Yu‐Chieh Lin, Min Lu, Carissa Rungkittikhun, Qi Zhang, Wei‐Shou Hu   +6 more
wiley   +1 more source

The Potential of Universal Primers for Barcoding of Subtropical Crops: Actinidia, Feijoa, Citrus, and Tea. [PDF]

Int J Mol Sci
Samarina LS, Koninskaya NG, Shkhalakhova RM, Simonyan TA, Tsaturyan GA, Shurkina ES, Kulyan RV, Omarova ZM, Tutberidze TV, Ryndin AV, Orlov YL.   +10 more
europepmc   +1 more source

Characterization of I-Ppo, an intron-encoded endonuclease that mediates homing of a group I intron in the ribosomal DNA of Physarum polycephalum.

, 1990
D E Muscarella, Erika L. Ellison, Birgit Ruoff, Volker M. Vogt   +3 more
openalex   +1 more source

First‐line serplulimab plus chemotherapy in extensive‐stage small‐cell lung cancer: Updated results and biomarker analysis from the ASTRUM‐005 randomized clinical trial

Cancer Communications, EarlyView.
Abstract Background The ASTRUM‐005 study previously demonstrated a significant overall survival (OS) benefit with serplulimab (a programmed death 1 inhibitor) plus chemotherapy versus chemotherapy alone in previously untreated extensive‐stage small‐cell lung cancer (ES‐SCLC).
Ying Cheng, Shuang Zhang, Liang Han, Lin Wu, Jun Chen, Peiyan Zhao, Hongmei Sun, Guilan Wen, Yinghua Ji, Anastasia Zimina, Jianhua Shi, Zhijie Pan, Jinsheng Shi, Xicheng Wang, Yuansong Bai, Tamar Melkadze, Yueyin Pan, Xuhong Min, Maksym Viguro, Xingya Li, Yanqiu Zhao, Junquan Yang, Tamta Makharadze, Ekaterine Arkania, Haoyu Yu, Jing Li, Fang Yang, Xinyi Yang, Chen Ling, Qingyu Wang, Yongqiang Shan, Jun Zhu, the ASTRUM‐005 Study Group   +32 more
wiley   +1 more source

DBR1 orchestrates the fate of lariat RNA: debranching-dependent turnover and function. [PDF]

Nucleic Acids Res
Tang Q, Liao D, Zheng B.
europepmc   +1 more source

N6‐methyladenosine‐regulated exosome biogenesis orchestrates an immunosuppressive pre‐metastatic niche in gastric cancer peritoneal metastasis

Cancer Communications, EarlyView.
Abstract Background Gastric cancer peritoneal metastasis is clinically challenging, given the limited treatment options and poor prognosis. The molecular mechanisms that precede gastric cancer peritoneal metastasis, known as the pre‐metastatic niche (PMN), and its relationship with N6‐methyladenosine (m6A) modification remain unclear.
Song Li, Jianyuan Zhou, Shuang Wang, Qian Yang, Shulun Nie, Chunwang Ji, Xue Zhang, Shuhan Li, Xuanyu Zhou, Jiahui Chu, Xuehui Wu, Jianqiao Jiao, Ruitao Xu, Qian Xu, Miao Huang, Qiushi Wang, Liliang Dou, Qinqin Hu, Fan Jiang, Xin Dai, Zhaodi Nan, Xinyu Song, Di Zhang, Lian Liu   +23 more
wiley   +1 more source