Results 271 to 280 of about 413,811 (335)

Natural Products Targeting Notch Signaling in Cancer: Mechanistic Insights and Food‐Based Chemoprevention Potential

Food Frontiers, EarlyView.
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima, Parteek Prasher, Mousmee Sharma, Dietrich Büsselberg, Gabriela Figueroa‐González, Octavio Daniel Reyes‐Hernández, Edgar Yebrán Villegas‐Vázquez, Hernán Cortés, Gerardo Leyva‐Gómez, Jesús Herrera‐Bravo, Solomon Habtemariam, Javad Sharifi‐Rad, Monica Butnariu, Cristian Berar, Angela Caunii, William C. Cho   +15 more
wiley   +1 more source

Meta-analyses of clozapine, norclozapine levels and their ratio across three genome wide association studies. [PDF]

Transl Psychiatry
Rask SM, Solismaa A, Ahola-Olli A, Molden E, O'Connell KS, Lyytikäinen LP, Mononen N, Lehtimäki T, Kampman O.   +8 more
europepmc   +1 more source

A group I intron in the small subunit ribosomal RNA gene fromNaegleria andersonissp.andersonistrain PPMFB-6

, 1992
T. Martin Embley, Patricia Dyal, Simon Kilvington   +2 more
openalex   +2 more sources

Modulating Neurotoxic Effects of Prenatal Chlorpyrifos Exposure Through Probiotic and Vitamin D Gestational Supplementation: Unexpected Effects on Neurodevelopment and Sociability

Food Frontiers, EarlyView.
This study investigates whether gestational probiotic and vitamin D supplementation can mitigate CPF effects in Wistar rats. While supplementation did not reverse CPF‐induced deficits, it induced notable neurodevelopmental changes in control animals, underscoring the need for further research on prenatal supplementation safety.
Mario Coca, Cristian Perez‐Fernandez, Ana C. Abreu, Ana M. Salmerón, Miguel Morales‐Navas, Diego Ruiz‐Sobremazas, Teresa Colomina, Ignacio Fernández, Fernando Sanchez‐Santed   +8 more
wiley   +1 more source

Clarification of the clinical significance of an intron variant in a case of Peutz-Jeghers syndrome with abnormal RNA splicing of STK11. [PDF]

Mol Cytogenet
Ishikawa A, Gotoh M, Ushiama M, Sakamoto H, Tanabe N, Watanabe T, Cho H, Yamada M, Sugano K, Shiraishi K, Hirata M, Yoshida T, Sakurai A.   +12 more
europepmc   +1 more source

Plant mitochondrial PORR proteins facilitate group II intron splicing by binding to distinct regions within their target introns. [PDF]

Nucleic Acids Res
Wang C, Quadrado M, Ngom T, Mireau H.
europepmc   +1 more source

The role of Arabidopsis Splicing Factor 30 in floral transition and the implications of its alternative splicing. [PDF]

Plant Physiol
Zhang D, Li M, Aslam MM, Huang M, Chen MX, Liu YG, Zhang J.   +6 more
europepmc   +1 more source

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries [PDF]

, 2018
Borecki, Ingrid, de las Fuentes, Lisa, et al.,, Feitosa, Mary F, Gu, C. Charles, Kraja, Aldi T, Li, Yize, Lin, Shiow, Province, Michael A, Rao, Daberru C, Sung, Yun J, Wang, Lihua, Williams, Christine, Wojczynski, Mary K   +13 more
core   +1 more source

Structural DNMT-nucleosome contacts are related to DNA methylation patterns. [PDF]

Epigenetics Chromatin
George K, Neininger K, Schmitz AE, Walter J, Helms V.   +4 more
europepmc   +1 more source

SIX INDEPENDENT LOSSES OF THE CHLOROPLAST DNArpl2 INTRON IN DICOTYLEDONS: MOLECULAR AND PHYLOGENETIC IMPLICATIONS

, 1991
Stephen R. Downie, Richard G. Olmstead, Gérard Zurawski, Douglas E. Soltis, Pamela S. Soltis, John C. Watson, Jeffrey D. Palmer   +6 more
openalex   +1 more source