Results 21 to 30 of about 245,400 (261)
Molecular Biotechnology, 2011 Eukaryotic gene expression relies on several complex molecular machineries that act in a highly coordinated fashion. These machineries govern all the different steps of mRNA maturation, from gene transcription and pre-mRNA processing in the nucleus to the export of the mRNA to the cytoplasm and its translation.
Skoko, Natasa +3 more
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mAbs, 2023 Introns are included in genes encoding therapeutic proteins for their well-documented function of boosting expression. However, mis-splicing of introns in recombinant immunoglobulin (IgG) heavy chain (HC) transcripts can produce amino acid sequence ...
Emma Kelsall +5 more
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Frontiers in Molecular Biosciences, 2021 An evolutionarily conserved feature of introns is their ability to enhance expression of genes that harbor them. Introns have been shown to regulate gene expression at the transcription and post-transcription level.
Katherine Dwyer +3 more
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Molecular Cell, 2019 Parenteau et al. (2019) and Morgan et al. (2019) showed that a subset of introns can work as non-coding RNAs that trap the spliceosome and decrease global splicing upon nutrient depletion in yeast, providing a new example of the functionality of introns, molecules that were previously assumed to be useless.
Michela, Zaffagni, Sebastian, Kadener
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An overview of RNA splicing and functioning of splicing factors in land plant chloroplasts
RNA Biology, 2022 RNA splicing refers to a process by which introns of a pre-mRNA are excised and the exons at both ends are joined together. Chloroplast introns are inherently self-splicing ribozymes, but over time, they have lost self-splicing ability due to the ...
Xuemei Wang +4 more
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Novel Genomic and Evolutionary Perspective of Cyanobacterial tRNAs
Frontiers in Genetics, 2017 Transfer RNA (tRNA) plays a central role in protein synthesis and acts as an adaptor molecule between an mRNA and an amino acid. A tRNA has an L-shaped clover leaf-like structure and contains an acceptor arm, D-arm, D-loop, anti-codon arm, anti-codon ...
Tapan K. Mohanta +3 more
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Intron or no intron: a matter for nuclear pore complexes [PDF]
Nucleus, 2015 Nuclear pore complexes (NPCs) have been shown to regulate distinct steps of the gene expression process, from transcription to mRNA export. In particular, mRNAs expressed from intron-containing genes are surveyed by a specific NPC-dependent quality control pathway ensuring that unspliced mRNAs are retained within the nucleus.
Amandine, Bonnet, Benoit, Palancade
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Veterinary Sciences, 2020 DNA methylation of different gene components, including different exons and introns, or different lengths of exons and introns is associated with differences in gene expression.
Xiao Wang, Haja N. Kadarmideen
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The phylogeography of red and yellow coppersmith barbets (Aves: Megalaima haemacephala)
Frontiers in Ecology and Evolution, 2014 Understanding the evolution of color in birds is important because it is used for both inter- and intra-specific communication and is often linked to other important traits including life history, behavior, immunology and mate choice.
Robert-Jan eDen Tex +2 more
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The Globin Gene Family in Arthropods: Evolution and Functional Diversity
Frontiers in Genetics, 2020 Globins are small heme-proteins that reversibly bind oxygen. Their most prominent roles in vertebrates are the transport and storage of O2 for oxidative energy metabolism, but recent research has suggested alternative, non-respiratory globin functions ...
Andreas Prothmann +8 more
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