Results 31 to 40 of about 401,804 (292)
RHD Genotypes in a Chinese Cohort of Pregnant Women
RHD variants in D¯ Chinese pregnant women arose difficulties in management during pregnancy. Therefore, this study aims to precisely manage D¯ pregnant women by evaluating the spectrum of RHD mutations in D¯ pregnant women and getting insight into the ...
Jianjun Zhang +17 more
doaj +1 more source
Introns are included in genes encoding therapeutic proteins for their well-documented function of boosting expression. However, mis-splicing of introns in recombinant immunoglobulin (IgG) heavy chain (HC) transcripts can produce amino acid sequence ...
Emma Kelsall +5 more
doaj +1 more source
An orchestrated intron retention program in meiosis controls timely usage of transcripts during germ cell differentiation [PDF]
Global transcriptome reprogramming during sper-matogenesis ensures timely expression of factors in each phase of male germ cell differentiation. Sper-matocytes and spermatids require particularly exten-sive reprogramming of gene expression to switch from
Alberdi, Antonio J. +9 more
core +2 more sources
An evolutionarily conserved feature of introns is their ability to enhance expression of genes that harbor them. Introns have been shown to regulate gene expression at the transcription and post-transcription level.
Katherine Dwyer +3 more
doaj +1 more source
Rapid Targeted Gene Disruption in Bacillus Anthracis [PDF]
Anthrax is a zoonotic disease recognized to affect herbivores since Biblical times and has the widest range of susceptible host species of any known pathogen.
Ellington, Andrew +9 more
core +3 more sources
An overview of RNA splicing and functioning of splicing factors in land plant chloroplasts
RNA splicing refers to a process by which introns of a pre-mRNA are excised and the exons at both ends are joined together. Chloroplast introns are inherently self-splicing ribozymes, but over time, they have lost self-splicing ability due to the ...
Xuemei Wang +4 more
doaj +1 more source
Intronization, de-intronization and intron sliding are rare in Cryptococcus [PDF]
Eukaryotic pre-mRNA gene transcripts are processed by the spliceosome to remove portions of the transcript, called spliceosomal introns. The spliceosome recognizes intron boundaries by the presence of sequence signals (motifs) contained in the actual transcript, thus sequence changes in the genome that affect existing splicing signals or create new ...
openaire +3 more sources
Novel Genomic and Evolutionary Perspective of Cyanobacterial tRNAs
Transfer RNA (tRNA) plays a central role in protein synthesis and acts as an adaptor molecule between an mRNA and an amino acid. A tRNA has an L-shaped clover leaf-like structure and contains an acceptor arm, D-arm, D-loop, anti-codon arm, anti-codon ...
Tapan K. Mohanta +3 more
doaj +1 more source
Organization and sequence of the gene encoding the human acrosin-trypsin inhibitor (HUSI-II) [PDF]
A complete cDNA encoding the acrosin-trypsin inhibitor, HUSI-II, was used as a probe to isolate genomic clones from a human placenta library. Three clones which cover the entire HUSI-II gene were isolated and characterized.
Abelson +28 more
core +1 more source
DNA methylation of different gene components, including different exons and introns, or different lengths of exons and introns is associated with differences in gene expression.
Xiao Wang, Haja N. Kadarmideen
doaj +1 more source

