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Prevalence and genetics of "de novo" MEN2 syndromes.

J Clin Endocrinol Metab
Casalini R, Romei C, Bottici V, Cappagli V, Tascini V, Matrone A, Prete A, Ciampi R, Ramone T, Elisei R.   +9 more
europepmc   +1 more source

The minor spliceosome is a master immune regulator

Johnson M, Russ-Silsby J, Blair P, Govier M, Bonfield G, Domingo-Vila C, EXE-T1D consortium, ATAC clinical consortium, Wakeling M, Oram R, Flanagan S, Tree T, Patel K, Hattersley A, De Franco E.   +14 more
europepmc   +1 more source

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Origin of introns by ‘intronization’ of exonic sequences

Trends in Genetics, 2008
The mechanisms of spliceosomal intron creation have proved elusive. Here we describe a new mechanism: the recruitment of internal exonic sequences ('intronization') in Caenorhabditis species. The numbers of intronization events and introns gained by other mechanisms are similar, suggesting that intronization significantly contributes to recent intron ...
Irimia, Manuel, Rukov, Jakob Lewin, Penny, David, Vinther, Jeppe, Garcia-Fernandez, Jordi, Roy, Scott William   +5 more
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Frühe Introns – späte Introns?

Biologie in unserer Zeit, 1995
AbstractIntrons nennt man Nucleinsäuresequenzen, die mitten in Genregionen eingefügt sind, letztlich aber nicht in Polypeptidsequenzen übersetzt werden. Auch Prokaryoten und sogar Viren können unterbrochene Gene besitzen, aber nur bei den Eukaryoten findet man die „klassischen”︁ Introns, die dort fast alle Strukturgene zerstückeln.
openaire   +2 more sources