ABSTRACT The current study aims to delineate the role of a novel anaplastic lymphoma kinase (ALK) transcript, ALKATI, in ovarian high‐grade serous carcinoma (HGSC). Overexpressed ALKATI exhibited both cytoplasmic and nuclear localization in HGSC cells, whereas full‐length ALK was predominantly cytoplasmic.
Ako Yokoi+4 more
wiley +1 more source
Interactive Bioinformatics Lab: Using Genomic Databases for Active Learning in Dentistry
Journal of Dental Education, EarlyView.
François Isnaldo Dias Caldeira+1 more
wiley +1 more source
Human-specific genomic evolution of a regulatory network enables fine-tuning of N-cadherin gene expression. [PDF]
Erdmann É+9 more
europepmc +1 more source
Prp16 enables efficient splicing of introns with diverse exonic consensus elements in the short-intron rich <i>Cryptococcus neoformans</i> transcriptome. [PDF]
Negi MS+3 more
europepmc +1 more source
Direct repeats found in the vicinity of intron splice sites. [PDF]
Rogers SO, Bendich AJ.
europepmc +1 more source
Escape from X-chromosome inactivation at KDM5C is driven by promoter-proximal DNA elements and enhanced by domain context. [PDF]
Peeters S+6 more
europepmc +1 more source
Sequence-dependent and -independent effects of intron-mediated enhancement learned from thousands of random introns. [PDF]
Kowal EJK+4 more
europepmc +1 more source
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Origin of introns by ‘intronization’ of exonic sequences
Trends in Genetics, 2008The mechanisms of spliceosomal intron creation have proved elusive. Here we describe a new mechanism: the recruitment of internal exonic sequences ('intronization') in Caenorhabditis species. The numbers of intronization events and introns gained by other mechanisms are similar, suggesting that intronization significantly contributes to recent intron ...
Irimia, Manuel+5 more
openaire +4 more sources
Frühe Introns – späte Introns?
Biologie in unserer Zeit, 1995AbstractIntrons nennt man Nucleinsäuresequenzen, die mitten in Genregionen eingefügt sind, letztlich aber nicht in Polypeptidsequenzen übersetzt werden. Auch Prokaryoten und sogar Viren können unterbrochene Gene besitzen, aber nur bei den Eukaryoten findet man die „klassischen”︁ Introns, die dort fast alle Strukturgene zerstückeln.
openaire +2 more sources