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Blood, 2013
In this issue of Blood, Yuan et al provide evidence that processing of the first intronic sequence within the von Willebrand factor (vWF) gene facilitates expression by endothelial cells regardless of the source of the intron, while intron processing is irrelevant for vWF expression by megakaryocytes.(1)
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In this issue of Blood, Yuan et al provide evidence that processing of the first intronic sequence within the von Willebrand factor (vWF) gene facilitates expression by endothelial cells regardless of the source of the intron, while intron processing is irrelevant for vWF expression by megakaryocytes.(1)
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Biochemical and Biophysical Research Communications, 2005
MicroRNAs (miRNAs), small single-stranded regulatory RNAs capable of interfering with intracellular mRNAs that contain partial complementarity, are useful for the design of new therapies against cancer polymorphism and viral mutation. MiRNA was originally discovered in the intergenic regions of the Caenorhabditis elegans genome as native RNA fragments ...
Shao-Yao, Ying, Shi-Lung, Lin
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MicroRNAs (miRNAs), small single-stranded regulatory RNAs capable of interfering with intracellular mRNAs that contain partial complementarity, are useful for the design of new therapies against cancer polymorphism and viral mutation. MiRNA was originally discovered in the intergenic regions of the Caenorhabditis elegans genome as native RNA fragments ...
Shao-Yao, Ying, Shi-Lung, Lin
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Cell Biology International, 2008
AbstractIntrons of plant tubulin genes are useful molecular tools to study IME (Intron Mediated Enhancement of gene expression) and to define plant genetic and evolutionary relationships through ILP (Intron Length Polymorphism). Here we show that the intron present within the 5′UTR sequence of some rice β‐tubulin genes can sustain IME in rice ...
Breviario D +4 more
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AbstractIntrons of plant tubulin genes are useful molecular tools to study IME (Intron Mediated Enhancement of gene expression) and to define plant genetic and evolutionary relationships through ILP (Intron Length Polymorphism). Here we show that the intron present within the 5′UTR sequence of some rice β‐tubulin genes can sustain IME in rice ...
Breviario D +4 more
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Current Biology, 1991
Accumulating evidence that introns are highly restricted in their phylogenetic distribution strongly supports the view that introns were inserted late in eukaryotic evolution into preformed genes and, hence, that exon-shuffling played no role in the assembly of primordial genes.
Jeffrey D. Palmer, John M. Logsdon
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Accumulating evidence that introns are highly restricted in their phylogenetic distribution strongly supports the view that introns were inserted late in eukaryotic evolution into preformed genes and, hence, that exon-shuffling played no role in the assembly of primordial genes.
Jeffrey D. Palmer, John M. Logsdon
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Intron Biology, Focusing on Group II Introns, the Ancestors of Spliceosomal Introns
2015Self-splicing group II introns are large ribozymes and mobile retroelements initially identified in the mitochondrial and chloroplast genomes of lower eukaryotes and plants and subsequently found in bacteria and archaea. Group II introns display structural, functional and mechanistic similarities to eukaryotic pre-mRNA nuclear introns, which may have ...
Francisco Martínez-Abarca +4 more
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Intron Splicing and Intron-mediated Enhanced Expression in Monocots
1992Publisher Summary The basic recognition sites (5 ‘ , 3‘, and branchpoint) for intron splicing in plants do not differ significantly from those of vertebrates. It is also demonstrated, by the mutations of splice-site recognition sequences, that the 5 ‘ GT or 3‘ AG dinucleotides are essential for proper splicing in monocots.
Ralph M. Sinibaldi, Irvin J. Mettler
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Exon-intron circular RNAs regulate transcription in the nucleus
Nature Structural &Molecular Biology, 2015Zhaoyong Li +17 more
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Intron-Mediated RNA Interference, Intronic MicroRNAs, and Applications
2010Nearly 97% of the human genome is non-coding DNA. The intron occupies most of it around the gene-coding regions. Numerous intronic sequences have been recently found to encode microRNAs (miRNAs), responsible for RNA-mediated gene silencing through RNA interference (RNAi)-like pathways.
Shao-Yao Ying +2 more
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Mobile Introns and Intron-Encoded Proteins
Science, 1989Ronald A. Butow, Philip S. Perlman
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Post-transcriptional splicing of nascent RNA contributes to widespread intron retention in plants
Nature Plants, 2020Jinbu Jia +11 more
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