Results 101 to 110 of about 304,363 (385)
Origin and evolution of spliceosomal introns
Biology Direct, 2012 Evolution of exon-intron structure of eukaryotic genes has been a matter of long-standing, intensive debate. The introns-early concept, later rebranded ‘introns first’ held that protein-coding genes were interrupted by numerous introns even at the ...
I. Rogozin +3 more
semanticscholar +1 more source
Advanced Materials, EarlyView.A novel immuno‐piezoelectric transducer is innovatively developed. This device promotes neural stem cell (NSC) differentiation and maturation via ultrasound‐induced electrical stimulation and it amplifies the therapeutic efficacy of NSC in traumatic brain injury (TBI) by modulating the immune microenvironment. This piezoelectric transducer with “immune‐
Linlin Liang +12 more
wiley +1 more source
A Quantitative Approach to Investigating the Hypothesis of Prokaryotic Intron Loss [PDF]
, 2011 Using a novel method, we show that ordered triplets of motifs usually associated with spliceosomal intron recognition are underrepresented in the protein coding sequence of complete Thermotogae, archaeal and bacterial genomes.
Robert M. Sinclair
core +1 more source
Intron Evolution in Saccharomycetaceae [PDF]
Genome Biology and Evolution, 2014 Introns in protein-coding genes are very rare in hemiascomycetous yeast genomes. It has been suggested that these species have experienced extensive intron loss during their evolution from the postulated intron-rich fungal ancestor. However, no intron-devoidy east species have been identified and some of the introns remaining within the genomes of ...
Hooks, Katarzyna B +2 more
openaire +3 more sources
Advanced Science, EarlyView.Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo +6 more
wiley +1 more source
BMC Genomics, 2019 Background In contrast to the highly labile mitochondrial (mt) genomes of vascular plants, the architecture and composition of mt genomes within the main lineages of bryophytes appear stable and invariant.
Shanshan Dong +9 more
doaj +1 more source
Evolutionary dynamics of U12-type spliceosomal introns
BMC Evolutionary Biology, 2010 Background Many multicellular eukaryotes have two types of spliceosomes for the removal of introns from messenger RNA precursors. The major (U2) spliceosome processes the vast majority of introns, referred to as U2-type introns, while the minor (U12 ...
Mount Stephen M +3 more
doaj +1 more source
Recent mobility of plastid encoded group II introns and twintrons in five strains of the unicellular red alga Porphyridium [PDF]
PeerJ, 2015 Group II introns are closely linked to eukaryote evolution because nuclear spliceosomal introns and the small RNAs associated with the spliceosome are thought to trace their ancient origins to these mobile elements.
Marie-Mathilde Perrineau +3 more
doaj +2 more sources
Characterization of serine proteinase expression in agaricus bisporus and coprinopsis cinerea by using green fluorescent protein and the A. bisporus SPR1 Promoter [PDF]
, 2008 The Agaricus bisporus serine proteinase 1 (SPR1) appears to be significant in both mycelial nutrition and senescence of the fruiting body.
Andy M. Bailey +13 more
core +4 more sources
Differential chromatin marking of introns and expressed exons by H3K36me3
Nature Genetics, 2008 Variation in patterns of methylations of histone tails reflects and modulates chromatin structure and function. To provide a framework for the analysis of chromatin function in Caenorhabditis elegans, we generated a genome-wide map of histone H3 tail ...
P. Kolasinska-Zwierz +5 more
semanticscholar +1 more source