Results 61 to 70 of about 304,363 (385)
An orchestrated intron retention program in meiosis controls timely usage of transcripts during germ cell differentiation [PDF]
, 2017 Global transcriptome reprogramming during sper-matogenesis ensures timely expression of factors in each phase of male germ cell differentiation. Sper-matocytes and spermatids require particularly exten-sive reprogramming of gene expression to switch from
Alberdi, Antonio J. +9 more
core +2 more sources
Mobile Introns Shape the Genetic Diversity of Their Host Genes
Genetics, 2016 Self-splicing introns populate several highly conserved protein-coding genes in fungal and plant mitochondria. In fungi, many of these introns have...
J. Repar, Tobias Warnecke
semanticscholar +1 more source
Non-coding parts of genomes as the basis of epigenetic heredity
Вавиловский журнал генетики и селекции, 2017 We hypothesized that the basis of epigenetic regulation of genomes in ontogenesis is the specificity of the distribution, number and composition of transposons. Transposons constitute the major part of the genomes of multicellular eukaryotes.
R. N. Mustafin, E. K. Khusnutdinova
doaj +1 more source
Genomic organization of nucleolin gene in carp fish: Evidence for several genes [PDF]
, 2006 http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000200017&lng=es&nrm=isoThe protein nucleolin, functionally involved in the main steps of ribosome biogenesis, is codified by a single copy gene in mammals.
Alvarez, Marco +5 more
core +2 more sources
Ecology and EvolutionUnderstanding the forces that shape population genetic structure is fundamental both for understanding evolutionary trajectories and for conservation. Many factors can influence the geographic distribution of genetic variation, and the extent to which ...
Bronwyn A. S. Harkness +3 more
doaj +1 more source
Proceedings, 2017 Information content of a polymeric macromolecule can be calculated in bits, by multiplying the number of building blocks that encompasses the entire length of the macromolecule with the Shannon’s entropy of each building block, which could be determined ...
Yekbun Adiguzel
doaj +1 more source
Analysis of intron sequence features associated with transcriptional regulation in human genes. [PDF]
PLoS ONE, 2012 Although some preliminary work has revealed the potential transcriptional regulatory function of the introns in eukaryotes, additional evidences are needed to support this conjecture.
Huimin Li, Dan Chen, Jing Zhang
doaj +1 more source
The gene coding for small ribosomal subunit RNA in the basidiomycete Ustilago maydis contains a group I intron [PDF]
, 1992 The nucleotide sequence of the gene coding for small ribosomal subunit RNA in the basidiomycete Ustilago maydis was determined. It revealed the presence of a group I intron with a length of 411 nucleotides.
De Wachter, Rupert +3 more
core +1 more source
Mammalian Introns: When the Junk Generates Molecular Diversity
International Journal of Molecular Sciences, 2015 Introns represent almost half of the human genome, yet their vast majority is eliminated from eukaryotic transcripts through RNA splicing. Nevertheless, they feature key elements and functions that deserve further interest.
F. Hubé, C. Francastel
semanticscholar +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source