Results 41 to 50 of about 210,665 (290)

Defining the location of promoter-associated R-loops at near-nucleotide resolution using bisDRIP-seq

eLife, 2017
R-loops are features of chromatin consisting of a strand of DNA hybridized to RNA, as well as the expelled complementary DNA strand. R-loops are enriched at promoters where they have recently been shown to have important roles in modifying gene ...
Jason G Dumelie, Samie R Jaffrey
doaj   +1 more source

Comparative Genomics Analysis of Ciliates Provides Insights on the Evolutionary History Within “Nassophorea–Synhymenia–Phyllopharyngea” Assemblage

Frontiers in Microbiology, 2019
Ciliated protists (ciliates) are widely used for investigating evolution, mostly due to their successful radiation after their early evolutionary branching.
Bo Pan, Bo Pan, Xiao Chen, Lina Hou, Qianqian Zhang, Zhishuai Qu, Zhishuai Qu, Alan Warren, Miao Miao   +8 more
doaj   +1 more source

The mitogenomes of Leptographium aureum, Leptographium sp., and Grosmannia fruticeta: expansion by introns

Frontiers in Microbiology, 2023
IntroductionMany members of the Ophiostomatales are of economic importance as they are bark-beetle associates and causative agents for blue stain on timber and in some instances contribute towards tree mortality.
Jigeesha Mukhopadhyay, Alvan Wai, Georg Hausner   +2 more
doaj   +1 more source

Horizontal Transfer and Gene Loss Shaped the Evolution of Alpha-Amylases in Bilaterians

G3: Genes, Genomes, Genetics, 2020
The subfamily GH13_1 of alpha-amylases is typical of Fungi, but it is also found in some unicellular eukaryotes (e.g., Amoebozoa, choanoflagellates) and non-bilaterian Metazoa.
Andrea Desiderato, Marcos Barbeitos, Clément Gilbert, Jean-Luc Da Lage   +3 more
doaj   +1 more source

The Cancer Spliceome: Reprograming of Alternative Splicing in Cancer

Frontiers in Molecular Biosciences, 2018
Alternative splicing allows for the expression of multiple RNA and protein isoforms from one gene, making it a major contributor to transcriptome and proteome diversification in eukaryotes.
Ettaib El Marabti, Ihab Younis
doaj   +1 more source

Rescue of splicing-mediated intron loss maximizes expression in lentiviral vectors containing the human ubiquitin C promoter. [PDF]

, 2014
Lentiviral vectors almost universally use heterologous internal promoters to express transgenes. One of the most commonly used promoter fragments is a 1.2-kb sequence from the human ubiquitin C (UBC) gene, encompassing the promoter, some enhancers, first
Cooper, Aaron R, Gschweng, Eric H, Kohn, Donald B, Lill, Georgia R   +3 more
core   +1 more source

In search of lost introns

, 2007
Many fundamental questions concerning the emergence and subsequent evolution of eukaryotic exon-intron organization are still unsettled. Genome-scale comparative studies, which can shed light on crucial aspects of eukaryotic evolution, require adequate ...
Adachi, Aldous, Altschul, Bieri, Blum, Carmel, Collins, Coulombe-Huntington, Csűrös, Csűrös, Devroye, Durbin, Edgar, Felsenstein, Felsenstein, Felsenstein, Friedman, Guindon, Harding, Heard, Hubbard, Igor B. Rogozin, IHBSC, J. Andrew Holey, Jeffares, Kececioglu, Kosakovsky Pond, Larget, Ma, Marchler-Bauer, McDiarmid, McKenzie, Miklós Csűrös, Müller, Nguyen, Nielsen, Nixon, Press, Pruitt, Raible, Rogozin, Rogozin, Rosenberg, Roy, Roy, Roy, Roy, Stamatakis, Steel, Sverdlov, Sverdlov, Tatusov, Vaňácová, Zhang   +53 more
core   +1 more source

An orchestrated intron retention program in meiosis controls timely usage of transcripts during germ cell differentiation [PDF]

, 2017
Global transcriptome reprogramming during sper-matogenesis ensures timely expression of factors in each phase of male germ cell differentiation. Sper-matocytes and spermatids require particularly exten-sive reprogramming of gene expression to switch from
Alberdi, Antonio J., Bielli, Pamela, De la Grange, Pierre, DI PERSIO, Sara, Geremia, Raffaele, Jolly, Ariane, Naro, Chiara, Sette, Claudio, Setterblad, Niclas, Vicini, Elena   +9 more
core   +2 more sources

Mitochondrial genomes of the early land plant lineage liverworts (Marchantiophyta): conserved genome structure, and ongoing low frequency recombination

BMC Genomics, 2019
Background In contrast to the highly labile mitochondrial (mt) genomes of vascular plants, the architecture and composition of mt genomes within the main lineages of bryophytes appear stable and invariant.
Shanshan Dong, Chaoxian Zhao, Shouzhou Zhang, Li Zhang, Hong Wu, Huan Liu, Ruiliang Zhu, Yu Jia, Bernard Goffinet, Yang Liu   +9 more
doaj   +1 more source

Stability domains of actin genes and genomic evolution

, 2007
In eukaryotic genes the protein coding sequence is split into several fragments, the exons, separated by non-coding DNA stretches, the introns. Prokaryotes do not have introns in their genome.
A. Dkhissi, B. Alberts, D. Poland, E. Carlon, J. W. Bizzaro, K. A. Marx, M. Lejard Malki, N. J. Dibb, R. Blossey, S. W. Roy   +9 more
core   +1 more source