Results 101 to 110 of about 555,600 (315)

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Mesiodens ile birlikte görülen bir intrüzyon olgusu: 30 aylık takip vaka sunumu

open access: yesEuropean Annals of Dental Sciences, 2010
İntrüziv lüksasyon, dişin alveoler kemik içerisine gömülmesi nedeniyle dişin destek yapıları ve pulpasında hasara yol açan bir travma tipidir. Mesiodens üst çene ön bölgede bulunan süpernümerer dişlerin en sık görülen tipidir.
Duygu Atıcı, Levent Özer
doaj  

EIDA: An Energy-Intrusion aware Data Aggregation Technique for Wireless Sensor Networks [PDF]

open access: yesJournal of Advances in Computer Engineering and Technology, 2016
Energy consumption is considered as a critical issue in wireless sensor networks (WSNs). Batteries of sensor nodes have limited power supply which in turn limits services and applications that can be supported by them.
Nafiseh Daneshgar   +3 more
doaj  

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

open access: yesMolecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva   +5 more
wiley   +1 more source

PERSPECTIVES AND LIMITS OF MANDIBULAR LATERAL INCISOR INTRUSION ASSOCIATED WITH PERIODONTAL DISEASE. A FEM STUDY

open access: yesRomanian Journal of Oral Rehabilitation, 2019
Introduction. FEM is a reliable tool for researching the impact of orthodontic therapy on the affected periodontal tissues. Material and methods. Using Catia V5R16 and Abaqus software we analysed various clinical scenarios for intruding the lateral ...
Ionut Luchian   +10 more
doaj  

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee   +9 more
wiley   +1 more source

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