Results 101 to 110 of about 700,206 (362)

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Lozenge tilings of hexagons with intrusions I: Generalized intrusion

Advances in Applied Mathematics
30 pages, 12 figures, Figures are updated and some minor errors are ...
Seok Hyun Byun, Tri Lai
openaire   +2 more sources

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Detection of Hacker Intention Using Deep Packet Inspection

Journal of Cybersecurity and Privacy
Ideally, in a real cyberattack, the early detection of probable hacker intent can lead to improved mitigation or prevention of exploitation. With the knowledge of basic principles of communication protocols, the reconnaissance/scanning phase intentions ...
Justin Foreman, Willie L. Waters, Charles A. Kamhoua, Ahmed H. Anwar Hemida, Jaime C. Acosta, Blessing C. Dike   +5 more
doaj   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Analysis of Clear Aligner Therapy Predictability for Mandibular Incisor Intrusion in Children and Adults

Applied Sciences
(1) The aim was to evaluate the predictability of treatment outcomes using clear aligner therapy (CAT) and ClinCheck Web 1.4 (Align Technology, Inc., San Jose, CA, USA) software in mandibular incisor intrusion in both children and adults with deep bite ...
Christopher Burns, Abdul Basir Barmak, Robert Tarby, Dimitrios Michelogiannakis, Paul Emile Rossouw   +4 more
doaj   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Comparative Evaluation of Intrusion with Different Techniques

Turkish Journal of Orthodontics, 2006
The aim of this study was to compare the effectiveness of two fixed appliance techniques, which are commonly used for correction of a deep overbite. The study comprised of 38 patients (19 boys and 19 girls) in the treatment group with deep overbite (+4mm)
Mustafa Erkan, Sedat Mandıracı, Mehmet Demir Yiğit   +2 more
doaj   +1 more source

Biomechanics Strategies for Space Closure in Deep Overbite

Journal of Dentistry Indonesia, 2013
Space closure is an interesting aspect of orthodontic treatment related to principles of biomechanics. It should be tailored individually based on patient’s diagnosis and treatment plan. Understanding the space closure biomechanics basis leads to achieve
Harryanto Wijaya, Isnani Jenie, Himawan Halim   +2 more
doaj   +1 more source

Network Intrusion Detection [PDF]

, 2011
Attacks against computers and the Internet are in the news every week. These primarily take the form of malicious code such as viruses and worms, or denial of service attacks. Less commonly reported are attacks which gain access to computers, either for the purpose of producing damage (such as defacing web sites or deleting data) or for the ...
openaire   +2 more sources