Results 101 to 110 of about 545,206 (314)

Unraveling intrusions

open access: yes, 2023
Traumatic events as happen in the context of the violence of war may cause the occurrence of intrusions – images or thoughts of such a traumatic event that arise spontaneously and involuntarily. This PhD thesis demonstrates that people can also experience intrusions about events they have not witnessed themselves.
openaire   +2 more sources

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Bridging the Gap From Caldera Unrest to Resurgence

open access: yesFrontiers in Earth Science, 2019
Calderas often inflate up to a few meters for weeks to years, which is evidence of short-term unrest. Some calderas also show larger uplift (up to a thousand meters), achieved over the long-term (hundreds to thousands of years), manifest by a resurgent ...
Valerio Acocella
doaj   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

The Moderating Factors of Click on Intrusive Online Advertising [PDF]

open access: yesJournal of Emerging Trends in Marketing and Management, 2017
The advent of new media such as Internet, has allowed the advertising communication a new boom. Now integrated into the communication strategy, online advertising is not only means of budgetary savings but also an essential tool for the brand and sales ...
FAKHIR, SARAH
doaj  

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

open access: yesMolecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva   +5 more
wiley   +1 more source

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