Results 111 to 120 of about 716,322 (331)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The Moderating Factors of Click on Intrusive Online Advertising [PDF]
Journal of Emerging Trends in Marketing and Management, 2017 The advent of new media such as Internet, has allowed the advertising communication a new boom. Now integrated into the communication strategy, online advertising is not only means of budgetary savings but also an essential tool for the brand and sales ...
FAKHIR, SARAH
doaj
Biomechanics Strategies for Space Closure in Deep Overbite
Journal of Dentistry Indonesia, 2013 Space closure is an interesting aspect of orthodontic treatment related to principles of biomechanics. It should be tailored individually based on patient’s diagnosis and treatment plan. Understanding the space closure biomechanics basis leads to achieve
Harryanto Wijaya +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Бюллетень сибирской медицины, 2002 The process of formation of a single government politics in the sphere of industrial property is discussed. It is pointed out that economical significance of the objects of IP is rising because of priority orientation of the Russian science and industry ...
N. G. Zubareva
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Frontiers in Earth ScienceRegional magnetic data in the southeastern segment of the Nigerian Niger Delta were evaluated with the aim of mapping deep-seated tectonic elements. Enhanced filtering operations and 3D forward modelling were applied on the magnetic data.
Ohara E. Eze +10 more
doaj +1 more source
Will the argues between an employee and an employer come to the end?
Бюллетень сибирской медицины, 2002 In the article the question of regulation of the relations between the employer and employers is discussed. With the aim to define these relations there was established, inner Thesis about the office inventions in Siberian State Medical University.
G. D. Tsesarskaya
doaj +1 more source
Intrusion Detection using Open Source Tools [PDF]
We have witnessed in the recent years that open source tools have gained popularity among all types of users, from individuals or small businesses to large organizations and enterprises.
Jack TIMOFTE
core