Results 131 to 140 of about 716,322 (331)

Root Resorptıon Durıng Bıcuspıd Intrusıon Wıth Varyıng Force Magnıtudes

open access: yesTurkish Journal of Orthodontics, 1996
This study was carried out on 14 upper first premolars the extractions of which were planned as a part of orthodontic treatment. Of 14 teeth, 10 formed the test group and 4, the control group. Three of the test teeth were intruded with a continuous force
Nazan Küçükkeleş   +2 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Replacement Of The Interocclusal Space Lost After Preparatıon Wıth An Orthodontıc Applıcatıon

open access: yesTurkish Journal of Orthodontics, 1988
Interocclusal space achieved by the preparation of the teeth for the fixed prosthetic restorations could be lost with the extrusion of those teeth when a considerable elapse of time happened to be between the preparation of the teeth and the cementation ...
Hakan N. İşcan   +2 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Management of a rare combination of dental trauma: A case report

open access: yesJournal of Indian Society of Pedodontics and Preventive Dentistry, 2007
The occurrence of combined injury of intrusion, avulsion and lateral luxation is rare and the mechanism responsible for this is intriguing. This case report describes such a combined injury and its management.
Suprabha B, Mogra S
doaj  

Comparative Evaluation of Intrusion with Different Techniques

open access: yesTurkish Journal of Orthodontics, 2006
The aim of this study was to compare the effectiveness of two fixed appliance techniques, which are commonly used for correction of a deep overbite. The study comprised of 38 patients (19 boys and 19 girls) in the treatment group with deep overbite (+4mm)
Mustafa Erkan   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Comparison of Intrusive Effects and Amount of Root Resorption in Maxillary Incisors Using Two Conventional Intrusion Arches and Mini-Implants

open access: yesJournal of Pharmacy and Bioallied Sciences
Aim and Objective: This study aimed to compare the amount of maxillary incisor intrusion and root resorption using three methods: mini-implants, utility arches, and Connecticut intrusion arches.
Shilpa Vinu   +5 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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