Results 101 to 110 of about 140,788 (314)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Mesiodens ile birlikte görülen bir intrüzyon olgusu: 30 aylık takip vaka sunumu

open access: yesEuropean Annals of Dental Sciences, 2010
İntrüziv lüksasyon, dişin alveoler kemik içerisine gömülmesi nedeniyle dişin destek yapıları ve pulpasında hasara yol açan bir travma tipidir. Mesiodens üst çene ön bölgede bulunan süpernümerer dişlerin en sık görülen tipidir.
Duygu Atıcı, Levent Özer
doaj  

Chemical Evolution of Intercumulus Liquid, as Recorded in Plagioclase Overgrowth Rims from the Skaergaard Intrusion

open access: yes
The intercumulus liquid of a crystal mush fills pore spaces, and typically solidifies to form overgrowths on cumulus grains and poikilitic post-cumulus minerals.
Humphreys, M. C. S.
core   +1 more source

Composições de IDSs: viabilizando o monitoramento de segurança em ambientes de larga escala [PDF]

open access: yes, 2007
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Tecnológico. Programa de Pós-Graduação em Engenharia ElétricaA crescente necessidade de compartilhamento de informações entre organizações parceiras ou membros de organizações virtuais ...
Brandão, José Eduardo Malta de Sá
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

EIDA: An Energy-Intrusion aware Data Aggregation Technique for Wireless Sensor Networks [PDF]

open access: yesJournal of Advances in Computer Engineering and Technology, 2016
Energy consumption is considered as a critical issue in wireless sensor networks (WSNs). Batteries of sensor nodes have limited power supply which in turn limits services and applications that can be supported by them.
Nafiseh Daneshgar   +3 more
doaj  

Detecção de intrusão usando técnicas de aprendizagem de máquinas [PDF]

open access: yes, 2010
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-graduação em Engenharia de Automação e Sistemas, Florianópolis, 2010Sistemas de detecção de intrusão (IDSs) têm sido projetados para analisar dados ...
Moll, Vinicius
core  

Intrusion Detection System - MDL driven

open access: yes, 2020
Intrusion Detection System - MDL driven R and Python ...
Serinelli, Benedetto Marco
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

An intrusion layer in stationary incompressible fluids Part 2: A solitary wave

open access: yes, 2006
The propagation of a solitary wave in a horizontal fluid layer is studied. There is an interfacial free surface above and below this intrusion layer, which is moving at constant speed through a stationary density-stratified fluid system.
Forbes, L.K., Hocking, G.C.
core  

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