Results 81 to 90 of about 140,788 (314)

THE EFFECT OF INTRUSION ON THE PHYSICAL AND CHEMICAL PROPERTIES OF COAL

open access: yesJGE
Coal is a deposit of organic matter derived from plant remains that have undergone diagenesis process to form a coal seams. This study aims to determine the impact of intrusion on the physical and chemical characteristics of coal.
Evan Rosyadi Ogara   +2 more
doaj   +1 more source

Bridging the Gap From Caldera Unrest to Resurgence

open access: yesFrontiers in Earth Science, 2019
Calderas often inflate up to a few meters for weeks to years, which is evidence of short-term unrest. Some calderas also show larger uplift (up to a thousand meters), achieved over the long-term (hundreds to thousands of years), manifest by a resurgent ...
Valerio Acocella
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

The Moderating Factors of Click on Intrusive Online Advertising [PDF]

open access: yesJournal of Emerging Trends in Marketing and Management, 2017
The advent of new media such as Internet, has allowed the advertising communication a new boom. Now integrated into the communication strategy, online advertising is not only means of budgetary savings but also an essential tool for the brand and sales ...
FAKHIR, SARAH
doaj  

Biomechanics Strategies for Space Closure in Deep Overbite

open access: yesJournal of Dentistry Indonesia, 2013
Space closure is an interesting aspect of orthodontic treatment related to principles of biomechanics. It should be tailored individually based on patient’s diagnosis and treatment plan. Understanding the space closure biomechanics basis leads to achieve
Harryanto Wijaya   +2 more
doaj   +1 more source

A note on the flow of a homogeneous intrusion into a two-layer fluid

open access: yes, 2007
The intrusion of a constant density fluid at the interface of a two-layer fluid is considered. Numerical solutions are computed for a model of a steady intrusion resulting from flow down a bank and across a broad lake or reservoir.
Forbes, L.K., Hocking, G.C.
core  

Anomaly Intrusion Detection based on Concept Drift

open access: yes, 2020
Nowadays, security on the internet is a vital issue and therefore, intrusion detection is one of the major research problems for networks that defend external attacks. Intrusion detection is a new approach for providing security in existing computers and
Gokul R   +3 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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