Results 61 to 70 of about 180,067 (246)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Intrusion Detection using Open Source Tools [PDF]
We have witnessed in the recent years that open source tools have gained popularity among all types of users, from individuals or small businesses to large organizations and enterprises.
Jack TIMOFTE
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Tafsir bil Ra'yi as Intrusion: The Debate between Ibn Taymiyyah and Ibn 'Ashur
QiSTQur'anic interpretation has undergone diverse methodological developments throughout Islamic intellectual history, one of which is tafsīr bi al-ra'y or interpretation based on reason and ijtihād.
Husna Nadia +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Bridging the Gap From Caldera Unrest to Resurgence
Frontiers in Earth Science, 2019 Calderas often inflate up to a few meters for weeks to years, which is evidence of short-term unrest. Some calderas also show larger uplift (up to a thousand meters), achieved over the long-term (hundreds to thousands of years), manifest by a resurgent ...
Valerio Acocella
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
A note on the flow of a homogeneous intrusion into a two-layer fluid [PDF]
, 2007 The intrusion of a constant density fluid at the interface of a two-layer fluid is considered. Numerical solutions are computed for a model of a steady intrusion resulting from flow down a bank and across a broad lake or reservoir.
Forbes, L.K., Hocking, G.C.
core
THE EFFECT OF INTRUSION ON THE PHYSICAL AND CHEMICAL PROPERTIES OF COAL
JGECoal is a deposit of organic matter derived from plant remains that have undergone diagenesis process to form a coal seams. This study aims to determine the impact of intrusion on the physical and chemical characteristics of coal.
Evan Rosyadi Ogara +2 more
doaj +1 more source